Ellipticine

CAS 519-23-3C17H14N2Biochemicals & Reagents

Ellipticine (CAS: 519-23-3; C17H14N2) is a synthetic compound with a molecular weight of 246.31 g/mol. It is recognised for its biological activity, particularly its role as an inhibitor of cytochrome P450 (CYP1A1) and DNA topoisomerase II. This compound is primarily utilised in biochemical research, especially in studies concerning apoptosis, cell cycle regulation, and DNA repair mechanisms. It is supplied by Tech Serve Solutions for laboratory and research applications.

IUPAC: 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole

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Ellipticine (C17H14N2) — chemical structure, CAS 519-23-3; Life Science, fine chemical supplied by Tech Serve Solutions

A to CApoptosis and Cell CycleBioactive Small MoleculesBiochemicals and ReagentsCell BiologyDNA Repair RegulatorsDNA metabolismEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymes

01 /Applications

Biochemical Research

Ellipticine serves as a valuable tool in biochemical research, aiding investigations into cellular processes such as apoptosis and cell cycle regulation. Its inhibitory effects on key enzymes like CYP1A1 and topoisomerase II make it crucial for studying DNA repair and cellular signalling pathways.

Enzyme Inhibition Studies

As a known inhibitor of Cytochrome P450 (CYP1A1) and DNA topoisomerase II, Ellipticine is frequently employed in studies focused on enzyme kinetics and drug metabolism. Researchers use it to understand the mechanisms by which these enzymes function and are regulated.

Cell Biology Investigations

This compound is utilized in cell biology to explore cellular responses to DNA damage and to investigate mechanisms of cell death. Its activity impacts DNA replication and repair, making it relevant for understanding cell proliferation and oncology research.

02 /Properties

Molecular weight	246.31
Empirical formula	C17H14N2
Storage temperature	2-8°C
Biological source	synthetic

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3462 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

519-23-3

MDL number

MFCD00010524

PubChem substance

24278416

Beilstein registry

221300

05 /Additional specifications

Gene Information	human ... CYP1A1(1543), CYP1A2(1544), KIT(3815), TOP2A(7153)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Ellipticine used for?

Ellipticine is primarily used in biochemical and cell biology research, particularly for studying apoptosis, cell cycle regulation, DNA repair, and as an inhibitor of Cytochrome P450 (CYP1A1) and DNA topoisomerase II.

What are the CAS number and formula for Ellipticine?

The CAS number for Ellipticine is 519-23-3, and its chemical formula is C17H14N2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Ellipticine for research purposes. The exact grade and purity are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade.

How should Ellipticine be handled safely?

Ellipticine is classified as toxic if swallowed and requires careful handling. Use appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge. Handle in a well-ventilated area and follow all safety data sheet guidelines. It carries a 'Danger' signal word with hazard statement H301.

Is Ellipticine a controlled substance?

The provided data does not indicate that Ellipticine is a controlled substance.

How is Ellipticine shipped and exported?

Ellipticine is shipped according to relevant transport regulations, identified as UN 3462, Class 6.1, Packing Group III. Tech Serve Solutions exports this chemical globally for research and laboratory use.

How can I request a sample or quote for Ellipticine?

To request a sample or a quotation for Ellipticine, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product CAS number 519-23-3.