Dodecanophenone
Dodecanophenone (CAS: 1674-38-0), with the molecular formula C6H5CO(CH2)10CH3 and a molecular weight of 260.41 g/mol, is a specialised organic ketone. It is primarily utilised as a marker in advanced analytical techniques such as micellar electrokinetic chromatography (MEKC) for the determination of partition coefficients, particularly for pharmaceuticals. This compound serves as a valuable building block in chemical synthesis.
- IUPAC
- 1-Phenyl-1-dodecanone
- Synonyms
- 1-Phenyl-1-dodecanone

Micellar Electrokinetic Chromatography (MEKC)
Dodecanophenone is employed as a standard or marker in MEKC systems. Its properties allow for the accurate characterisation of micellar environments within the chromatographic system.
Partition Coefficient Determination
This compound facilitates the determination of octanol-water partition coefficients of pharmaceuticals. Its use in pressure-assisted MEC aids in understanding drug lipophilicity and behaviour.
Organic Synthesis
As a ketone with a long alkyl chain, Dodecanophenone acts as a versatile building block in organic synthesis, enabling the construction of more complex molecules.
| Molecular weight | 260.41 |
|---|---|
| Linear formula | C6H5CO(CH2)10CH3 |
| Assay | 98% |
| Boiling point | 214-215 °C/16 mmHg(lit.) |
| Application | Dodecanophenone has been employed as micellar marker in:• micellar electrokinetic chromatography (MEC) systems1• determination of octanol-water partition coefficients of pharmaceuticals by using pressure-assisted MEC2 |
| Melting point | 45-47 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dodecanophenone used for?
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Dodecanophenone (CAS: 1674-38-0) is used as a marker in micellar electrokinetic chromatography (MEKC) and for determining the octanol-water partition coefficients of pharmaceuticals. It also serves as a building block in organic synthesis.
What is the CAS number and chemical formula for Dodecanophenone?
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The CAS number for Dodecanophenone is 1674-38-0, and its chemical formula is C6H5CO(CH2)10CH3.
What grade and purity does Tech Serve Solutions supply for Dodecanophenone?
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Tech Serve Solutions supplies Dodecanophenone with a minimum purity of 98%. This is a technical grade suitable for research and general chemical applications. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Dodecanophenone?
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Dodecanophenone has a flash point above 113 °C (235.4 °F) and is classified with WGK Germany 3. Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Avoid open flames and high temperatures.
How is Dodecanophenone packed, shipped, and exported by Tech Serve Solutions?
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Tech Serve Solutions expertly packs, ships, and exports Dodecanophenone globally, adhering to all relevant international shipping and safety regulations for chemical compounds.
How can I request a sample or quote for Dodecanophenone?
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To request a sample or obtain a quote for Dodecanophenone, please contact our sales team through the website or directly via email, providing your required quantity and shipping details.
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