Dodecanoyl chloride
Dodecanoyl chloride (CAS: 112-16-3) is an organic acid halide with the linear formula CH3(CH2)10COCl and a molecular weight of 218.76 g/mol. This compound serves as a key intermediate in organic synthesis, primarily used for acylating amines and alcohols to form amides and esters, respectively. Its reactivity makes it valuable in the production of surfactants, polymers, and pharmaceutical precursors.
- IUPAC
- Lauroyl chloride
- Synonyms
- Lauroyl chlorideDodecanoyl chlorideLauric acid chloride1-Dodecanoyl chloriden-Dodecanoyl chloriden-Dodecanoyl-ClAcid, dodecanoic, 1-chloro-1-oxoc-
Organic Synthesis Intermediate
Dodecanoyl chloride is widely employed as an acylating agent in organic chemistry. It readily reacts with nucleophiles such as amines and alcohols to introduce the dodecanoyl (lauryl) group, forming amides and esters, respectively, which are important functional groups in many complex molecules.
Surfactant Production
The compound is utilised in the synthesis of various surfactants. By reacting with appropriate substrates, it can be incorporated into molecules that exhibit surface-active properties, finding use in detergents, emulsifiers, and wetting agents.
Polymer Chemistry
Dodecanoyl chloride can act as a monomer or functionalising agent in polymerisation processes. It can be used to modify polymer properties or to create specialised polymers with specific characteristics.
Pharmaceutical Precursor Synthesis
This acid chloride serves as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and other biologically relevant molecules. Its ability to form ester and amide linkages is crucial in constructing complex pharmaceutical structures.
| Molecular weight | 218.76 |
|---|---|
| Linear formula | CH3(CH2)10COCl |
| Assay | ≥97.5% (GC) |
| Grade | purum |
| Boiling point | 134-137 °C/11 mmHg(lit.) |
| Density | 0.922 g/mL at 20 °C |
| Refractive index | n20/D 1.445 |
| Melting point | -13--10 °C |
| Solubility | methanol: soluble100 mg/mL, clear |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 140 °C / 284 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dodecanoyl chloride used for?
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Dodecanoyl chloride is primarily used as an acylating agent in organic synthesis for the production of amides and esters. It finds applications in the synthesis of surfactants, polymers, and pharmaceutical precursors.
What is the CAS number and formula for Dodecanoyl chloride?
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The CAS number for Dodecanoyl chloride is 112-16-3 and its linear formula is CH3(CH2)10COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dodecanoyl chloride with a purity of ≥97.5% (GC) and a grade of purum. We do not represent this product as USP, BP, or EP grade.
How is Dodecanoyl chloride safely handled and stored?
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Dodecanoyl chloride is corrosive and causes severe skin burns and eye damage (H314). It also causes respiratory irritation (H335). Handling requires full protective equipment including face shields, gloves, and appropriate respirators. Store in a well-ventilated place. Keep container tightly closed.
How is Dodecanoyl chloride packed and exported?
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Dodecanoyl chloride is packed according to international shipping regulations for hazardous materials (UN 3265, Class 8, PG II). Tech Serve Solutions is a global supplier and exporter, ensuring compliant packaging and documentation for international shipments.
How can I request a quote or sample for Dodecanoyl chloride?
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To request a quote or sample for Dodecanoyl chloride, please contact our sales team through the website or by calling our customer service line. Please specify the quantity required.
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