Dobutamine hydrochloride
Dobutamine hydrochloride (CAS: 49745-95-1), with the molecular formula C18H23NO3 · HCl and a molecular weight of 337.84, is a synthetic catecholamine analogue. It functions as a direct-acting adrenergic agonist, primarily stimulating beta-1 and beta-2 adrenergic receptors. This action leads to increased cardiac output and contractility with minimal effects on heart rate, making it valuable in specific cardiovascular applications.
- IUPAC
- (±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride
Cardiogenic Shock Management
Dobutamine hydrochloride is utilised in the treatment of severe heart failure and cardiogenic shock. It helps to improve cardiac output and tissue perfusion by increasing myocardial contractility.
Cardiac Stress Testing
This compound serves as a pharmacological agent in dobutamine stress echocardiography. It is used to induce myocardial stress, aiding in the diagnosis of coronary artery disease.
Research Chemical
As a bioactive small molecule, dobutamine hydrochloride is employed in research settings to investigate adrenergic receptor function and cardiovascular physiology.
| Molecular weight | 337.84 |
|---|---|
| Empirical formula | C18H23NO3 · HCl |
| Assay | ≥98% |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-20/21/22 |
| Safety statements (S) | 22-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRB1(153) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is dobutamine hydrochloride used for?
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Dobutamine hydrochloride is used for the short-term treatment of cardiac decompensation resulting from such conditions as myocardial infarction or open-heart surgery, and for cardiogenic shock. It is also used in dobutamine stress echocardiography.
What are the CAS number and formula for dobutamine hydrochloride?
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The CAS number for dobutamine hydrochloride is 49745-95-1, and its molecular formula is C18H23NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies dobutamine hydrochloride with an assay of ≥98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should dobutamine hydrochloride be handled and stored?
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Handle dobutamine hydrochloride with appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C. It is classified with hazard statements H302, H312, H332 (Harmful if swallowed, in contact with skin or if inhaled) and H361 (Suspected of damaging fertility or the unborn child).
Is dobutamine hydrochloride a controlled substance?
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Dobutamine hydrochloride is not listed as a controlled substance in the provided data. However, it is classified as Xn (Harmful) with risk statements R63 (Possible risk of harm to the unborn child) and R20/21/22 (Harmful by inhalation, in contact with skin and if swallowed).
How is dobutamine hydrochloride shipped?
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Dobutamine hydrochloride is typically shipped under controlled temperature conditions (2-8°C) to maintain its integrity. TSS exports this chemical globally.
How can I request a quote or sample?
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To request a quote or a sample of dobutamine hydrochloride, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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