Dithizone
Dithizone (CAS 60-10-6), with the linear formula C6H5NHNHCSN=NC6H5 and a molecular weight of 256.33, is a complex organic compound recognised for its utility as a reagent. It is particularly valued in analytical chemistry for its ability to form coloured chelates with various metal ions. This property makes it instrumental in spectrophotometric determination of trace metals, serving key roles in environmental analysis and industrial quality control.
- IUPAC
- Diphenylthiocarbazone
- Synonyms
- Diphenylthiocarbazone1,5-Diphenylthiocarbazone3-Phenyl-1-(phenylthiocarbamoyl)triazene

Metal Ion Detection
Dithizone is widely employed as a chelating agent for the colorimetric and spectrophotometric determination of numerous metal ions, including lead, mercury, cadmium, and zinc. Its ability to form intensely coloured complexes allows for sensitive quantification.
Analytical Reagent
In analytical laboratories, Dithizone serves as a critical reagent for the qualitative and quantitative analysis of trace metals in various matrices, such as water, biological samples, and industrial products. Its specific reactivity with certain metals is crucial for selective detection.
Histology and Staining
Dithizone finds application in histology as a stain, particularly for the visualisation of certain metal deposits within tissue samples. Its use in techniques related to hematology and histology aids in microscopic examination.
Chemical Synthesis
As an organic building block, Dithizone can participate in chemical synthesis, contributing its unique thiocarbonyl and diazo functionalities to the creation of more complex molecular structures.
| Molecular weight | 256.33 |
|---|---|
| Linear formula | C6H5NHNHCSN=NC6H5 |
| Assay | ≥85.0% |
| Grade | JIS special grade |
| Melting point | 168 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Cation traces | heavy metals: ≤0.002% |
| Ignition residue | ≤0.3% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Availability | available only in Japan |
|---|---|
| Absorbance Ratio | A ≥1.55 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dithizone used for?
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Dithizone (CAS 60-10-6) is primarily used as an analytical reagent for the colorimetric and spectrophotometric determination of various metal ions, including lead, mercury, and cadmium. It also finds applications in histology and chemical synthesis.
What are the CAS number and formula for Dithizone?
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The CAS number for Dithizone is 60-10-6, and its linear formula is C6H5NHNHCSN=NC6H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dithizone in JIS special grade with an assay of ≥85.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling Dithizone?
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Dithizone is classified with GHS07 and carries a 'Warning' signal word. It is labelled with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
Is Dithizone available for export?
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Dithizone (CAS 60-10-6) is available for export, though specific grades like the JIS special grade are noted as available only in Japan. Please contact us for international availability and shipping details.
How can I request a sample or quote for Dithizone?
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To request a sample or a quote for Dithizone, please utilise the inquiry form on our website or contact our sales department directly. Provide your contact details and the specific product information, including the CAS number 60-10-6.
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