Dimethylphenylsilanol

CAS 5272-18-4(C6H5)Si(OH)(CH3)2Chemical Synthesis

Dimethylphenylsilanol (CAS: 5272-18-4) is an organosilicon compound with the molecular formula (C6H5)Si(OH)(CH3)2 and a molecular weight of 152.27 g/mol. This silanol serves as a valuable silicon nucleophile, particularly in palladium-catalyzed cross-coupling reactions. Its specific properties make it a useful reagent in organic synthesis and materials science research.

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Dimethylphenylsilanol ((C6H5)Si(OH)(CH3)2) — chemical structure, CAS 5272-18-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisOrganometallic ReagentsOrganosiliconSilanols

01 /Applications

Palladium-Catalyzed Cross-Coupling

Dimethylphenylsilanol acts as a useful silicon nucleophile in palladium-catalyzed cross-coupling reactions, enabling the formation of new carbon-silicon bonds.

Organosilicon Chemistry

As a functionalized silanol, it contributes to the diverse field of organosilicon chemistry, facilitating the synthesis of complex silicon-containing molecules.

Chemical Synthesis Reagent

Its reactive hydroxyl group and phenylsilyl moiety make it a versatile building block for various synthetic transformations in research and development.

02 /Properties

Molecular weight	152.27
Linear formula	(C6H5)Si(OH)(CH3)2
Assay	95%
Density	0.975 g/mL at 25 °C
Refractive index	n20/D 1.514
Storage temperature	2-8°C
Application	A useful silicon nucleophile for Pd-catalyzed cross-coupling.1

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Flash point	91 °C / 195.8 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

5272-18-4

MDL number

MFCD08276879

PubChem substance

24884882

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Dimethylphenylsilanol used for?

Dimethylphenylsilanol is used as a silicon nucleophile in Pd-catalyzed cross-coupling reactions and as a versatile reagent in chemical synthesis, particularly within organosilicon chemistry.

What is the CAS number and formula for Dimethylphenylsilanol?

The CAS number is 5272-18-4 and the linear formula is (C6H5)Si(OH)(CH3)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Dimethylphenylsilanol with an assay of 95%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.

How should Dimethylphenylsilanol be handled safely?

Warning: Causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US). Ensure good ventilation and avoid contact with eyes and skin. Refer to the Safety Data Sheet for full handling instructions.

How is Dimethylphenylsilanol packed and shipped?

Dimethylphenylsilanol is stored at 2-8°C. While specific packing details vary, TSS ensures products are appropriately packaged for safe domestic and international export, adhering to all relevant regulations.