2,2′-Thiodiacetic acid
2,2′-Thiodiacetic acid (CAS: 123-93-3), with the linear formula S(CH₂COOH)₂, is a dicarboxylic acid featuring a sulfur atom linking two acetate groups. This organic compound, with a molecular weight of 150.15 g/mol, serves as a valuable building block in organic synthesis. It is commonly employed in the chemical industry as a reagent for introducing thioacetic acid moieties or in the preparation of sulfur-containing heterocyclic compounds and polymers.
- IUPAC
- 2,2′-Thio-bis(acetic acid),Dicarboxydimethyl sulfide,Thiodiglycolic acid
- Synonyms
- 2,2′-Thio-bis(acetic acid)Dicarboxydimethyl sulfideThiodiglycolic acid

Organic Synthesis Intermediate
2,2′-Thiodiacetic acid is utilised as a versatile intermediate in the synthesis of more complex organic molecules. Its difunctional nature allows for various chemical transformations, particularly in the formation of sulfur-containing compounds.
Building Block for Heterocycles
The compound is employed in the construction of heterocyclic ring systems, which are prevalent in pharmaceuticals and materials science. The sulfur atom provides a key structural element for these syntheses.
Precursor for Polymers
It can act as a monomer or comonomer in the synthesis of specific polymers, introducing sulfur atoms into the polymer backbone to modify properties such as thermal stability or refractive index.
| Molecular weight | 150.15 |
|---|---|
| Linear formula | S(CH2COOH)2 |
| Assay | 98% |
| Melting point | 128-131 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2′-Thiodiacetic acid used for?
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2,2′-Thiodiacetic acid is primarily used as an intermediate and building block in organic synthesis, particularly for creating sulfur-containing organic molecules and heterocyclic compounds. It also finds application in the synthesis of certain polymers.
What is the CAS number and chemical formula for 2,2′-Thiodiacetic acid?
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The CAS number for 2,2′-Thiodiacetic acid is 123-93-3, and its linear formula is S(CH₂COOH)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2′-Thiodiacetic acid with a purity of 98%. This product is suitable for research and general chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should 2,2′-Thiodiacetic acid be handled safely?
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2,2′-Thiodiacetic acid is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection (e.g., N100 or P3 filters), must be worn. Handle in a well-ventilated area and follow specific European safety statements (26-36/37/39-45).
How is 2,2′-Thiodiacetic acid packed and shipped?
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This chemical is shipped as UN 3261, hazard class 8, Packing Group II. Specific packaging details are available upon request, and TSS exports globally.
How can I request a sample or quote for 2,2′-Thiodiacetic acid?
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To request a sample or obtain a quotation for 2,2′-Thiodiacetic acid, please contact our sales department via the website or provide your requirements directly.
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