Dimethyl methylphosphonate
Dimethyl methylphosphonate (CAS: 756-79-6), with the formula CH3P(O)(OCH3)2 and a molecular weight of 124.08 g/mol, is a chemical reagent utilized in organic synthesis. It functions as a key component in C-C bond formation and olefination reactions, particularly in the Horner-Wadsworth-Emmons reaction. This compound is supplied by Tech Serve Solutions with an assay of 97%, suitable for various chemical synthesis applications.
- IUPAC
- Dimethoxymethyl phosphine oxide,Fyrol DMMP,Methanephosphonic acid dimethyl ester,NSC 62240,Reoflam DMMP

Reagent for Ketophosphonate Synthesis
Dimethyl methylphosphonate serves as a crucial reagent in the conversion of esters to ketophosphonates. This application is vital for constructing complex organic molecules.
Horner-Wadsworth-Emmons Reagent
This compound is employed as a reagent in the Horner-Wadsworth-Emmons reaction, a method for synthesizing alkenes from carbonyl compounds. It facilitates C-C bond formation through olefination.
General Chemical Synthesis
As a versatile synthetic reagent, Dimethyl methylphosphonate finds application in broader chemical synthesis pathways. Its reactivity allows for diverse transformations in organic chemistry.
| Molecular weight | 124.08 |
|---|---|
| Linear formula | CH3P(O)(OCH3)2 |
| Assay | 97% |
| Boiling point | 181 °C(lit.) |
| Density | 1.145 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |
| Vapour pressure | <0.1 mmHg (20 °C) |
| Application | Reagent used in the conversion of esters to ketophosphonates.1,2,3 |

Hazard statements
- H319Causes serious eye irritation
- H332Harmful if inhaled
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 69 °C / 156.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 46-36 |
| Safety statements (S) | 53-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dimethyl methylphosphonate used for?
+
Dimethyl methylphosphonate (CAS: 756-79-6) is primarily used as a reagent in organic synthesis, notably for the conversion of esters to ketophosphonates and in Horner-Wadsworth-Emmons olefination reactions for C-C bond formation.
What is the CAS number and chemical formula for Dimethyl methylphosphonate?
+
The CAS number for Dimethyl methylphosphonate is 756-79-6, and its chemical formula is CH3P(O)(OCH3)2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Dimethyl methylphosphonate with an assay of 97%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should Dimethyl methylphosphonate be handled safely?
+
Dimethyl methylphosphonate is classified as a Warning with hazards including H319 (Causes serious eye irritation) and H332 (Harmful if inhaled). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., a multi-purpose combination respirator cartridge or type ABEK filter), should be used. Handle in a well-ventilated area.
Is Dimethyl methylphosphonate a controlled substance?
+
The provided data does not indicate that Dimethyl methylphosphonate (CAS: 756-79-6) is a controlled substance.
How is Dimethyl methylphosphonate shipped and exported by TSS?
+
Dimethyl methylphosphonate is shipped and exported according to relevant transport regulations (RID/ADR: NA 1993 / PGIII). Please contact TSS for specific shipping and export details for your region.
How can I request a sample or quote for Dimethyl methylphosphonate?
+
To request a sample or a quote for Dimethyl methylphosphonate, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis