Diisopropylamine
Diisopropylamine (CAS: 108-18-9) is a secondary amine with the linear formula (CH₃)₂CHNHCH(CH₃)₂ and a molecular weight of 101.19 g/mol. This colourless liquid is known for its strong ammoniacal odour and is widely employed as a basic catalyst and building block in organic synthesis. Its applications span various chemical processes, primarily where a sterically hindered, non-nucleophilic base is required.
- IUPAC
- DIPA
- Synonyms
- DIPAIsopropylamine, N-isopropyl-N,N-Diisopropylethylamine2-Propanamine, N-(1-methylethyl)-
Organic Synthesis Reagent
Diisopropylamine serves as a strong, sterically hindered organic base in various synthetic transformations. It is frequently used as an acid scavenger and to promote reactions such as deprotonations and eliminations where selectivity is crucial.
Pharmaceutical Intermediate Synthesis
This amine is a valuable intermediate in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs). Its hindered nature allows for controlled reactions in multi-step syntheses.
Catalysis
Due to its basic properties, diisopropylamine finds application as a catalyst in certain chemical reactions, facilitating processes that require alkaline conditions.
Chemical Manufacturing
It is used in the production of various chemicals, including pesticides and rubber accelerators, leveraging its reactivity and structural characteristics.
| Molecular weight | 101.19 |
|---|---|
| Linear formula | (CH3)2CHNHCH(CH3)2 |
| Assay | ≥98.0% |
| Boiling point | 84 °C(lit.) |
| Density | 0.722 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.392(lit.) |
| Vapour pressure | 50 mmHg (20 °C) |
| Melting point | −61 °C(lit.) |
| Vapour density | 3.5 (vs air) |
| Autoignition temp | 599 °F |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 1158 8(3) / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-20/22-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diisopropylamine used for?
+
Diisopropylamine (CAS: 108-18-9) is primarily used as a sterically hindered organic base and reagent in chemical synthesis, particularly in the pharmaceutical and agricultural chemical industries. It also serves as an intermediate and catalyst in various chemical manufacturing processes.
What is the CAS number and formula for Diisopropylamine?
+
The CAS number for Diisopropylamine is 108-18-9, and its linear formula is (CH₃)₂CHNHCH(CH₃)₂.
What grade and purity does Tech Serve Solutions supply for Diisopropylamine?
+
Tech Serve Solutions supplies Diisopropylamine with an assay of ≥98.0%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated in the product documentation.
How should Diisopropylamine be handled safely?
+
Diisopropylamine is a highly flammable liquid and vapour (H225), harmful if swallowed (H302), causes severe skin burns and eye damage (H314), and harmful if inhaled (H332). Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, face shields, and respiratory protection (type ABEK). Keep away from heat, sparks, and open flames (P210).
Is Diisopropylamine a controlled substance?
+
Based on the provided data, Diisopropylamine (CAS: 108-18-9) is not indicated as a controlled substance.
How is Diisopropylamine packed and shipped?
+
Diisopropylamine is typically packed in accordance with international shipping regulations for hazardous materials. UN 1158, Hazard Class 8(3), Packing Group II designation indicates it is shipped as a corrosive and flammable liquid.
How can I request a sample or quote for Diisopropylamine?
+
To request a sample or quote for Diisopropylamine, please contact the Tech Serve Solutions sales team via our website or through your established account manager.
▶ Related products
5-Sulfosalicylic acid dihydrate
HO3SC6H3-2-(OH)CO2H 2H2O
Acids & Bases
Calcium hydroxide
Ca(OH)2
Acids & Bases
Acetic acid-12C2
12CH312CO2H
Acids & Bases
Acetic acid-13C2
13CH313CO2H
Acids & Bases
Acetic acid-13C2,d4
Acids & Bases
Acetic acid-17O2
CH3C17O2H
Acids & Bases
Acetic acid-18O2
CH3C18O2H
Acids & Bases
Acetic acid-2,2,2-d3
2-d3
Acids & Bases▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis