α,α-Difluorophenylacetic acid
α,α-Difluorophenylacetic acid (CAS 360-03-2), with the molecular formula C8H6F2O2 and a molecular weight of 172.13 g/mol, is a specialised fluorinated organic building block. This carboxylic acid derivative is primarily utilised in chemical synthesis as a key intermediate. Its difluorinated phenylacetic structure makes it valuable for introducing specific fluorine functionalities into more complex molecules, finding application in the development of pharmaceuticals and advanced materials.
- Synonyms
- 2,2-Difluoro-2-phenylacetic acid

Chemical Synthesis Intermediate
Utilised as a building block in organic synthesis, particularly for the introduction of the difluorophenylacetyl moiety into target molecules. Its structure is relevant in the development of novel compounds.
Pharmaceutical Research
Serves as an intermediate in the synthesis pathways for potential pharmaceutical agents. The incorporation of fluorine atoms can significantly alter the pharmacokinetic properties of drug candidates.
Materials Science
Can be employed in the synthesis of specialised polymers or materials where fluorination imparts desired properties such as thermal stability or altered surface characteristics.
| Molecular weight | 172.13 |
|---|---|
| Empirical formula | C8H6F2O2 |
| Assay | 97% |
| Melting point | 65-75 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α,α-Difluorophenylacetic acid used for?
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α,α-Difluorophenylacetic acid (CAS 360-03-2) is primarily used as a building block in organic synthesis, particularly for introducing difluorinated phenylacetyl groups into other molecules, with applications in pharmaceutical research and materials science.
What is the CAS number and molecular formula for α,α-Difluorophenylacetic acid?
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The CAS number for α,α-Difluorophenylacetic acid is 360-03-2, and its molecular formula is C8H6F2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies α,α-Difluorophenylacetic acid with an assay of 97%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the specifications.
How should α,α-Difluorophenylacetic acid be handled?
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α,α-Difluorophenylacetic acid is a Warning substance, classified with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Does TSS export α,α-Difluorophenylacetic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including α,α-Difluorophenylacetic acid.
How can I request a quote or sample for α,α-Difluorophenylacetic acid?
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To request a quote or sample for α,α-Difluorophenylacetic acid, please contact our sales department through the website or via direct email, providing your specific requirements.
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