Diethylenetriaminepentaacetic acid dianhydride
Diethylenetriaminepentaacetic acid dianhydride (CAS: 23911-26-4, C14H19N3O8) is a highly reactive organic compound with a molecular weight of 357.32 g/mol. It serves as a valuable building block in chemical synthesis, particularly for introducing strong chelating groups. This dianhydride is predominantly utilized as a reagent for protein modification and structural analysis, enabling precise functionalization through its ability to react with amino groups.
- IUPAC
- DTPA anhydride,DTPA dianhydride
- Synonyms
- DTPA anhydride,DTPA dianhydride
Protein Modification Reagent
Diethylenetriaminepentaacetic acid dianhydride is employed to covalently attach chelating groups to proteins. This modification is crucial for applications requiring metal ion binding, such as in protein structural studies or the development of metal-containing biomolecules.
Bioconjugation and Labelling
This compound facilitates the conjugation of DTPA (diethylenetriaminepentaacetic acid) moieties onto biomolecules, including proteins and peptides. Such conjugations are valuable for diagnostic imaging, radiopharmaceutical development, and targeted drug delivery systems.
Chemical Synthesis Intermediate
As a reactive anhydride, it acts as an organic building block in the synthesis of more complex molecules. Its structure allows for reactions with nucleophiles, making it useful in the preparation of functionalized materials and compounds.
Proteomics Research
In proteomics, this reagent can be used for specific amino acid modification, particularly lysine residues, enabling advanced techniques for protein characterization and analysis within complex biological systems.
| Molecular weight | 357.32 |
|---|---|
| Empirical formula | C14H19N3O8 |
| Assay | 98% |
| Storage temperature | −20°C |
| Application | Reagent for introducing a strong chelator onto proteins. |
| Melting point | 182-184 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethylenetriaminepentaacetic acid dianhydride used for?
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Diethylenetriaminepentaacetic acid dianhydride is primarily used as a reagent for introducing strong chelating groups onto proteins, aiding in protein modification, structural analysis, bioconjugation, and proteomics research.
What are the CAS number and formula for Diethylenetriaminepentaacetic acid dianhydride?
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The CAS number is 23911-26-4 and the empirical formula (Hill notation) is C14H19N3O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethylenetriaminepentaacetic acid dianhydride with an assay of 98%. This product is not represented as USP, BP, EP, or pharmaceutical grade.
How should Diethylenetriaminepentaacetic acid dianhydride be handled safely?
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Due to its irritant properties (H315, H319, H335), handle with appropriate personal protective equipment including a dust mask (N95 US standard), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is Diethylenetriaminepentaacetic acid dianhydride packed and shipped?
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This product requires storage at -20°C. It is exported by Tech Serve Solutions according to standard chemical handling and shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of Diethylenetriaminepentaacetic acid dianhydride, please contact our sales team through the website or via direct inquiry, providing your details and requirements.
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