PAC-1
PAC-1 (CAS 315183-21-2), a bioactive small molecule with the formula C23H28N4O2 and a molecular weight of 392.49 g/mol, is supplied by Tech Serve Solutions. This compound is primarily utilized in research concerning apoptosis and cell cycle regulation, particularly as a potent and selective inducer of apoptosis via activation of caspase-3. Its application extends to cell signaling studies within neuroscience research.
- IUPAC
- (4-Benzylpiperazino)acetic acid (3-allyl-2-hyroxybenzylidene)hydrazide,1-Piperazineacetic acid, 2-(phenylmethyl)-,[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hyrrazide
Apoptosis Research
PAC-1 serves as a crucial research tool for investigating the mechanisms of programmed cell death, specifically by activating caspase-3, a key executioner caspase. Its selectivity allows for targeted studies into apoptotic pathways.
Cell Cycle Regulation Studies
This compound is employed in research aimed at understanding the intricate processes of the cell cycle and how its dysregulation contributes to various cellular abnormalities and diseases.
Cell Signaling Investigations
PAC-1 is valuable for researchers studying intracellular signaling cascades, providing insights into how cellular communication networks influence cell fate decisions.
Neuroscience Research
As a modulator of cell signaling, PAC-1 finds applications in neuroscience research, potentially aiding in the study of neuronal cell death and survival mechanisms.
| Molecular weight | 392.49 |
|---|---|
| Empirical formula | C23H28N4O2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: ≥10 mg/mLdeionized water: ≤2 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36/37/38-50/53 |
| Safety statements (S) | 26-36/37-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PAC-1 used for?
+
PAC-1 is primarily used in research for its potent ability to induce apoptosis by activating caspase-3. It is applied in studies of apoptosis, cell cycle regulation, cell signaling, and neuroscience.
What are the CAS number and formula for PAC-1?
+
The CAS number for PAC-1 is 315183-21-2, and its empirical formula is C23H28N4O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies PAC-1 with an assay of ≥98% (HPLC). This product is intended for research use and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the primary safety concerns when handling PAC-1?
+
PAC-1 is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302, H315, H319, H335). It is also very toxic to aquatic life with long-lasting effects (H400). Appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area and avoid release into the environment.
How is PAC-1 packaged and shipped?
+
PAC-1 is typically supplied as a white solid. Shipments are handled in compliance with relevant dangerous goods regulations (UN 3077, Class 9, PG III), and it is exported globally by Tech Serve Solutions.
How can I request a sample or quote for PAC-1?
+
To request a sample or obtain a quote for PAC-1, please contact the Tech Serve Solutions sales team through our website or direct contact channels.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis