Dichloro[(R)-(+)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl][(2R)-(−)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium
Dichloro[(R)-(+)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl][(2R)-(−)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium (CAS: 329735-86-6) is a chiral ruthenium complex with a molecular weight of 1109.07 g/mol. This compound is primarily utilised as a highly effective catalyst in asymmetric synthesis, particularly for hydrogenation reactions. Its unique chiral structure enables precise control over stereochemistry, making it an invaluable tool in the synthesis of enantiomerically pure compounds for pharmaceutical and fine chemical industries.
- Synonyms
- 1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium,329735-86-6, C63H58Cl2N2O2P2Ru
![Dichloro[(R)-(+)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl][(2R)-(−)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium (C63H58Cl2N2O2P2Ru) — chemical structure, CAS 329735-86-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F329735-86-6.png&w=3840&q=75)
Asymmetric Hydrogenation Catalysis
This ruthenium complex serves as a powerful chiral catalyst for asymmetric hydrogenation of various unsaturated substrates. It facilitates the stereoselective addition of hydrogen, leading to the formation of chiral centres with high enantiomeric excess.
Synthesis of Pharmaceutical Intermediates
Its ability to control stereochemistry makes it crucial in the multi-step synthesis of complex pharmaceutical intermediates. This ensures the production of enantiomerically pure active pharmaceutical ingredients (APIs) with the desired biological activity.
Chiral Ligand Development
The compound incorporates BINAP and a chiral diamine ligand, showcasing its role in developing sophisticated catalytic systems. These ligands are essential for achieving high selectivity and efficiency in catalysed reactions.
Fine Chemical Manufacturing
Utilised in the production of fine chemicals where precise stereochemical control is paramount. This includes the synthesis of agrochemicals, fragrances, and advanced materials requiring specific chiral properties.
| Molecular weight | 1109.07 |
|---|---|
| Empirical formula | C63H58Cl2N2O2P2Ru |
| Assay | 95% |
| Optical activity | [α]20/D +593°, c = 0.5 in methylene chloride |
| Storage temperature | −20°C |
| Melting point | 180 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichloro[(R)-(+)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl][(2R)-(−)-1,1-bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine]ruthenium used for?
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This compound is primarily used as a chiral catalyst in asymmetric synthesis, particularly for hydrogenation reactions, enabling the stereoselective synthesis of enantiomerically pure compounds.
What is the CAS number and formula for this ruthenium complex?
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The CAS number is 329735-86-6. The empirical formula is C63H58Cl2N2O2P2Ru.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 95%. We do not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling requirements for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter due to its hazardous nature (WGK Germany: 3).
How is this chemical shipped or exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of handling international shipments with appropriate documentation and adherence to shipping regulations.
How can I request a sample or a quote?
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Please contact our sales team directly through the website or by phone to request a sample or a formal quotation for this product.
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