Dichloro-methyl-octadecylsilane
Dichloro-methyl-octadecylsilane (CAS 5157-75-5, C19H40Cl2Si) is a silicon-based chemical compound with a molecular weight of 367.51 g/mol. It functions as a valuable reagent in chemical synthesis, particularly in protection and derivatization strategies. This organosilicon compound offers unique properties for organic chemistry applications.
- IUPAC
- Methyl-octadecyl-dichlorosilane,Octadecyl-methyl-dichlorosilane
- Synonyms
- Methyl-octadecyl-dichlorosilaneOctadecyl-methyl-dichlorosilane

Protecting Group Chemistry
Dichloro-methyl-octadecylsilane can be employed to introduce the octadecylmethylsilyl protecting group onto various organic molecules. This group offers specific solubility and chromatographic properties during multi-step syntheses.
Derivatization Reagent
It serves as a derivatizing agent, converting analytes into more volatile or detectable forms for techniques such as gas chromatography. The long alkyl chain can influence separation characteristics.
Surface Modification
Organosilanes like this are often investigated for modifying the surface properties of materials, such as silica or glass. The long octadecyl chain can impart hydrophobicity.
Chemical Synthesis
As a specialized reagent, it plays a role in various synthetic pathways where the introduction of a methyl-octadecylsilyl moiety is required. Its reactivity is governed by the two chlorine atoms attached to silicon.
| Molecular weight | 367.51 |
|---|---|
| Empirical formula | C19H40Cl2Si |
| Assay | ≥90% (GC) |
| Boiling point | 185 °C/2.5 mmHg(lit.) |
| Density | 0.92 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.457(lit.)n20/D 1.457 |
| Melting point | ~25 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 185 °C / 365 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichloro-methyl-octadecylsilane used for?
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Dichloro-methyl-octadecylsilane is primarily used as a reagent in chemical synthesis, specifically for protection and derivatization strategies in organic chemistry. It can also be applied in surface modification.
What is the CAS number and formula for Dichloro-methyl-octadecylsilane?
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The CAS number is 5157-75-5 and the empirical formula is C19H40Cl2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dichloro-methyl-octadecylsilane with an assay of ≥90% (GC). This product is not supplied as USP, BP, or EP grade.
What are the safety and handling considerations for this compound?
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This compound is classified as dangerous (Danger, H314) and causes severe skin burns and eye damage. Appropriate personal protective equipment, including faceshields, gloves, and suitable respirators, must be used. Handle only in a well-ventilated area.
How is Dichloro-methyl-octadecylsilane packed, shipped, and exported?
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The product is shipped as UN 2987, Class 8, Packing Group II, according to stringent international regulations for hazardous materials. TSS is experienced in global export.
How can I request a quote or sample?
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To request a quote or a sample, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (5157-75-5).
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