Dibenzocyclooctyne-PEG4-biotin conjugate
Dibenzocyclooctyne-PEG4-biotin conjugate (CAS: 1255942-07-4, C39H51N5O8S) is a versatile chemical probe incorporating a strained alkyne for bioorthogonal cycloadditions and a biotin tag for detection and immobilization. Its PEG4 linker provides water solubility and spacing. This high-value reagent is primarily employed in chemical biology for applications such as activity-based protein profiling and the visualisation of newly synthesised proteins.
- IUPAC
- DBCO-PEG4-biotin
- Synonyms
- DBCO-PEG4-biotin

Activity-Based Protein Profiling (ABPP)
This conjugate is valuable for ABPP, allowing researchers to identify and profile enzyme activities within complex biological systems by selectively labelling active proteins.
Detection of Newly Synthesized Proteins
It facilitates the visual identification and study of nascent protein synthesis in living cells or organisms, providing insights into proteome dynamics.
Biomolecule Immobilization
The biotin moiety enables the straightforward immobilization of azide-labeled biomolecules onto avidin or streptavidin-coated surfaces for various biochemical assays and purification strategies.
| Molecular weight | 749.92 |
|---|---|
| Empirical formula | C39H51N5O8S |
| Storage temperature | −20°C |
| Application | • activity-based protein profiling• detection of newly synthesized proteins• immobilization of azide-labeled biomolecules |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dibenzocyclooctyne-PEG4-biotin conjugate used for?
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Dibenzocyclooctyne-PEG4-biotin conjugate is used in chemical biology for activity-based protein profiling, detection of newly synthesized proteins, and immobilization of azide-labeled biomolecules.
What are the CAS number and chemical formula for Dibenzocyclooctyne-PEG4-biotin conjugate?
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The CAS number is 1255942-07-4 and the empirical formula is C39H51N5O8S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research purposes. The specific grade and purity are available on the Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations?
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This compound is classified under WGK Germany 3, indicating it is hazardous to water. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area, avoiding release into the environment.
How is this product shipped and exported?
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Dibenzocyclooctyne-PEG4-biotin conjugate is typically shipped and exported under controlled temperature conditions (e.g., -20°C) to maintain product integrity. Please contact us for specific shipping and export details.
How can I request a sample or quote?
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To request a sample or a quotation for Dibenzocyclooctyne-PEG4-biotin conjugate, please contact our sales department via the website or provide your details through the product enquiry form.
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