Dibenzocyclooctyne-amine
Dibenzocyclooctyne-amine (CAS: 1255942-06-3), with the empirical formula C18H16N2O and a molecular weight of 276.33 g/mol, is a key amine-functionalised cyclooctyne derivative. This compound is instrumental in chemical biology and conjugation chemistry, particularly for strain-promoted copper-free azide-alkyne cycloaddition (CuAAC) reactions. It facilitates the formation of stable triazole linkages without the need for a metal catalyst, making it valuable for complex molecular assembly.
- IUPAC
- DBCO-NH2,DBCO-amine
- Synonyms
- DBCO-NH2, DBCO-amine
Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC)
Dibenzocyclooctyne-amine participates in copper-free click chemistry reactions. Its strained cyclooctyne ring readily reacts with azides, enabling the efficient formation of triazole linkages essential for bioconjugation and materials science.
Bioconjugation Chemistry
This reagent is widely used to conjugate molecules like peptides, proteins, or nucleic acids that have been functionalised with azide groups. The amine functionality allows for further derivatisation or direct attachment to biomolecules.
Chemical Synthesis
As a versatile building block, Dibenzocyclooctyne-amine can be incorporated into complex organic molecules. Its unique reactivity profile makes it useful in developing novel chemical entities for research and development.
| Molecular weight | 276.33 |
|---|---|
| Empirical formula | C18H16N2O |
| Storage temperature | −20°C |
| Application | Amine functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. |
| Melting point | 86-96 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dibenzocyclooctyne-amine used for?
+
Dibenzocyclooctyne-amine is primarily used in strain-promoted copper-free azide-alkyne cycloaddition (SPAAC) reactions for bioconjugation, chemical synthesis, and materials science, enabling the formation of stable triazole linkages without a metal catalyst.
What are the CAS number and formula for Dibenzocyclooctyne-amine?
+
The CAS number for Dibenzocyclooctyne-amine is 1255942-06-3, and its empirical formula is C18H16N2O.
What grade and purity does Tech Serve Solutions supply for Dibenzocyclooctyne-amine?
+
Tech Serve Solutions supplies Dibenzocyclooctyne-amine. The specific grade and purity are typically detailed on the Certificate of Analysis. For research purposes, it is supplied as a laboratory reagent, and TSS does not represent it as USP, BP, or EP grade.
How should Dibenzocyclooctyne-amine be handled and stored?
+
Dibenzocyclooctyne-amine should be stored at −20°C. Refer to the Safety Data Sheet for comprehensive handling, safety, and disposal information, paying close attention to any indicated hazards.
How are products like Dibenzocyclooctyne-amine packed and shipped?
+
Dibenzocyclooctyne-amine is carefully packed according to international shipping regulations for chemical substances. TSS is experienced in exporting fine chemicals globally.
How can I request a sample or quote for Dibenzocyclooctyne-amine?
+
To request a sample or a quote for Dibenzocyclooctyne-amine, please contact the TSS sales department through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis