Perfluoroheptanoic acid
Perfluoroheptanoic acid (CAS: 375-85-9), with the molecular formula CF3(CF2)5CO2H and a molar mass of 364.06 g/mol, is a fully fluorinated carboxylic acid. It serves as a valuable intermediate and building block in various chemical synthesis processes, particularly within fluorous chemistry and for the development of Rf-tagged compounds. Its unique properties make it suitable for specialized synthetic applications requiring fluorinated moieties.
- IUPAC
- Perfluoroheptanoic acid,Tridecafluoroheptanoic acid

Fluorous Synthesis
Perfluoroheptanoic acid is employed as a key reagent or building block in fluorous synthesis, enabling the facile separation and purification of reaction products through fluorous phase techniques.
Specialty Chemical Synthesis
This compound acts as a precursor for introducing perfluoroheptanoyl groups into more complex molecules, finding use in the synthesis of specialty chemicals with tailored properties.
Rf-Tagged Building Blocks
It is utilised in the construction of Rf-tagged molecules, which are valuable tools in combinatorial chemistry and drug discovery for purification and characterisation.
Surface Modification
Derivatives of perfluoroheptanoic acid may be explored for surface modification applications, imparting unique hydrophobic and oleophobic characteristics.
| Molecular weight | 364.06 |
|---|---|
| Linear formula | CF3(CF2)5CO2H |
| Assay | 99% |
| Boiling point | 175 °C/742 mmHg(lit.) |
| Density | 1.792 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.306(lit.) |
| Melting point | 30 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Perfluoroheptanoic acid used for?
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Perfluoroheptanoic acid is primarily used in fluorous synthesis and as a building block for Rf-tagged compounds and other specialty chemicals requiring fluorinated moieties.
What are the CAS number and formula for Perfluoroheptanoic acid?
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The CAS number is 375-85-9 and the chemical formula is CF3(CF2)5CO2H.
What grade and purity does Tech Serve Solutions supply for Perfluoroheptanoic acid?
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Tech Serve Solutions supplies Perfluoroheptanoic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Perfluoroheptanoic acid be handled safely?
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Perfluoroheptanoic acid is dangerous; it causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection, must be used. Handle only in well-ventilated areas and seek immediate medical attention if contact occurs. Refer to the Safety Data Sheet for full details.
Is Perfluoroheptanoic acid a controlled substance?
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The provided data does not indicate that Perfluoroheptanoic acid is a controlled substance.
How is Perfluoroheptanoic acid packed, shipped, and exported?
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Perfluoroheptanoic acid is packed according to stringent safety and regulatory standards for transportation. TSS exports chemicals globally, adhering to all relevant international shipping regulations.
How can I request a sample or quote for Perfluoroheptanoic acid?
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To request a sample or a quote for Perfluoroheptanoic acid, please contact our sales department through the website or by phone, providing your specific requirements.
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