Di(N-succinimidyl) oxalate
Di(N-succinimidyl) oxalate (CAS: 57296-03-4), with the molecular formula C10H8N2O8 and a molecular weight of 284.18 g/mol, is a valuable reagent. It functions as an active ester primarily used in chemical synthesis, particularly in peptide coupling reactions and for activating carboxyl groups. This compound is supplied by TSS for research and development purposes, offering reliable performance in various organic chemistry applications.
- IUPAC
- N,N′-Disuccinimidyl oxalate,DSO
Peptide Synthesis
Di(N-succinimidyl) oxalate serves as an efficient coupling reagent in peptide synthesis, facilitating the formation of amide bonds between amino acids. Its use is crucial for constructing peptide chains in research and pharmaceutical development.
Carboxyl Group Activation
This compound is employed to activate carboxylic acids, converting them into reactive N-hydroxysuccinimide esters. These activated esters are then readily available for nucleophilic substitution reactions, enabling the synthesis of various derivatives.
Chemical Biology Research
In chemical biology, Di(N-succinimidyl) oxalate can be utilized for bioconjugation and labeling studies. Its ability to form stable ester linkages makes it suitable for modifying biomolecules.
Organic Synthesis Reagent
As a versatile synthetic reagent, it finds application in a range of organic transformations requiring the introduction of oxalate functionalities or the formation of ester linkages under mild conditions.
| Molecular weight | 284.18 |
|---|---|
| Empirical formula | C10H8N2O8 |
| Assay | ≥97.0% (T) |
| Grade | purum |
| Melting point | 239 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Di(N-succinimidyl) oxalate used for?
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Di(N-succinimidyl) oxalate is primarily used as a coupling reagent in peptide synthesis and for the activation of carboxylic acids in organic synthesis and chemical biology research.
What is the CAS number and formula for Di(N-succinimidyl) oxalate?
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The CAS number is 57296-03-4 and the molecular formula is C10H8N2O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Di(N-succinimidyl) oxalate with an assay of ≥97.0% (T), classified as purum grade. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for Di(N-succinimidyl) oxalate?
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Di(N-succinimidyl) oxalate is classified with GHS07 (Warning) and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Always handle in a well-ventilated area and avoid breathing dust.
How is Di(N-succinimidyl) oxalate packed, shipped, and exported?
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Tech Serve Solutions offers Di(N-succinimidyl) oxalate in various pack sizes suitable for laboratory and industrial requirements. We are experienced global exporters of fine chemicals and reagents.
How can I request a quote or sample of Di(N-succinimidyl) oxalate?
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To request a quote or a sample of Di(N-succinimidyl) oxalate, please visit the product page on our website or contact our sales team directly.
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