Dantrolene sodium salt
Dantrolene sodium salt (CAS: 14663-23-1; Formula: C14H9N4NaO5; MW: 336.23) is a hydantoin derivative known for its ability to modulate intracellular calcium release. It functions as a ryanodine receptor antagonist, impacting calcium homeostasis in cells. This compound is recognised for its approved therapeutic applications, particularly in managing malignant hyperthermia and certain types of muscle spasticity.
- IUPAC
- 1-[(5-(p-Nitrophenyl)furfurylidene)amino]hydantoin sodium salt
- Synonyms
- 1-[(5-p-Nitrophenyl)furfurylidene]amino]hydantoin sodium salt
Malignant Hyperthermia Treatment
Dantrolene sodium salt is a critical therapeutic agent for the emergency treatment of malignant hyperthermia, a severe reaction that can occur under general anaesthesia.
Muscle Spasticity Management
It is also employed to reduce muscle spasticity associated with conditions such as spinal cord injury, multiple sclerosis, and stroke.
Research Tool in Cell Biology
As a specific intracellular calcium regulator, Dantrolene sodium salt serves as a valuable research tool for studying calcium signaling pathways and cellular responses.
| Molecular weight | 336.23 |
|---|---|
| Empirical formula | C14H9N4NaO5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dantrolene sodium salt used for?
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Dantrolene sodium salt is used therapeutically for the emergency treatment of malignant hyperthermia and to manage muscle spasticity. It is also utilised in research as a cell signalling modulator.
What are the CAS number and formula for Dantrolene sodium salt?
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The CAS number for Dantrolene sodium salt is 14663-23-1, and its molecular formula is C14H9N4NaO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dantrolene sodium salt as a research chemical. We do not represent it as USP, BP, or EP grade. Please refer to the product specifications for available assay information.
What are the safety considerations for Dantrolene sodium salt?
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Dantrolene sodium salt is classified under WGK 2 in Germany, indicating it is hazardous to water. Appropriate safety precautions and handling procedures should be followed as per its Safety Data Sheet.
How is Dantrolene sodium salt packed and shipped?
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Dantrolene sodium salt is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a quote or sample for Dantrolene sodium salt?
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To request a quote or a sample of Dantrolene sodium salt, please contact our sales department via the website or your dedicated account manager.
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