D-(−)-Pantolactone
D-(−)-Pantolactone (CAS: 599-04-2), a chiral organic compound with the molecular formula C6H10O3 and a molecular weight of 130.14 g/mol, is a vital chiral building block. It is primarily utilised in asymmetric synthesis and chemical manufacturing processes. Its specific optical activity ([α]20/D −51±2°) highlights its stereochemical importance in producing enantiomerically pure compounds for various advanced applications.
- IUPAC
- (R)-(−)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone,(R)-(−)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone,(R)-(−)-Pantolactone,Pantoic acid γ-lactone
- Synonyms
- (R)-(−)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone(R)-(−)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone(R)-(−)-PantolactonePantoic acid γ-lactone
Asymmetric Synthesis
D-(−)-Pantolactone serves as a key chiral intermediate in the stereoselective synthesis of complex molecules. Its inherent chirality allows for the construction of enantiomerically enriched products critical in pharmaceutical and fine chemical industries.
Pharmaceutical Intermediates
This lactone is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). It contributes a defined stereocentre necessary for the biological activity of certain drug compounds.
Chiral Building Block
As an organic building block, D-(−)-Pantolactone offers a readily available source of a specific stereochemistry. It is valuable for researchers and manufacturers requiring chiral synthons for novel compound development.
| Molecular weight | 130.14 |
|---|---|
| Empirical formula | C6H10O3 |
| Assay | ≥99.0% (T) |
| Boiling point | 120-122 °C/15 mmHg(lit.) |
| Optical activity | [α]20/D −51±2°, c = 3% in H2O |
| Storage temperature | 2-8°C |
| Melting point | 89-92 °C91 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-(−)-Pantolactone used for?
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D-(−)-Pantolactone is primarily used in asymmetric synthesis and as a chiral building block for the production of complex organic molecules, including pharmaceutical intermediates.
What is the CAS number and chemical formula for D-(−)-Pantolactone?
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The CAS number is 599-04-2, and the empirical formula is C6H10O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-(−)-Pantolactone with an assay of ≥99.0% (T). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should D-(−)-Pantolactone be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Recommended storage is at 2-8°C.
Is D-(−)-Pantolactone a controlled substance?
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Based on the provided data, D-(−)-Pantolactone is not indicated as a controlled substance. WGK Germany classification is 1.
How is D-(−)-Pantolactone packed, shipped, and exported?
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Products are carefully packed according to industry standards for safe transport. Tech Serve Solutions is experienced in global export and logistics for fine chemicals.
How can I request a sample or quote for D-(−)-Pantolactone?
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Please contact our sales department via the website or direct inquiry channels to request a sample or a formal quotation.
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