D-(+)-Norephedrine hydrochloride
D-(+)-Norephedrine hydrochloride (CAS: 40626-29-7; Formula: C9H13NO · HCl; MW: 187.67 g/mol) is a chiral alkaloid derivative of ephedrine. It functions as a valuable intermediate in organic synthesis, particularly in asymmetric synthesis and as a chiral auxiliary. This compound is utilised in research settings for its stereochemical properties and its role in the development of novel chemical entities. Tech Serve Solutions supplies this chemical for laboratory and industrial research purposes.
- IUPAC
- (+)-Phenylpropanolamine hydrochloride,(1S,2R)-2-Amino-1-phenyl-1-propanol hydrochloride

Chiral Auxiliary in Asymmetric Synthesis
D-(+)-Norephedrine hydrochloride serves as an effective chiral auxiliary in asymmetric synthesis. Its well-defined stereochemistry allows for the induction of chirality in various organic reactions, facilitating the synthesis of enantiomerically pure compounds.
Building Block for Pharmaceutical Intermediates
This compound is employed as a key building block in the synthesis of complex pharmaceutical intermediates. Its structural features make it suitable for incorporation into diverse molecular frameworks, supporting drug discovery and development.
Research in Chemical Biology
D-(+)-Norephedrine hydrochloride finds application in chemical biology research, enabling studies on stereoselective processes and the development of novel chemical probes. Its use aids in understanding biological pathways and designing new therapeutic agents.
| Molecular weight | 187.67 |
|---|---|
| Empirical formula | C9H13NO · HCl |
| Assay | ≥98.0% (AT) |
| Optical activity | [α]/D +33.0±1.0°, c = 7 in H2O |
| Melting point | 172-175 °C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-(+)-Norephedrine hydrochloride used for?
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D-(+)-Norephedrine hydrochloride is used as a chiral auxiliary in asymmetric synthesis, a building block for pharmaceutical intermediates, and in chemical biology research.
What is the CAS number and chemical formula for D-(+)-Norephedrine hydrochloride?
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The CAS number is 40626-29-7, and the chemical formula is C9H13NO · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-(+)-Norephedrine hydrochloride with an assay of ≥98.0% (AT). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for D-(+)-Norephedrine hydrochloride?
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D-(+)-Norephedrine hydrochloride is classified as harmful if swallowed (H302). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
Is D-(+)-Norephedrine hydrochloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including D-(+)-Norephedrine hydrochloride.
How can I request a sample or quote for D-(+)-Norephedrine hydrochloride?
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To request a sample or quote, please contact our sales team through the website or by phone. We will be pleased to assist you.
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