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D-(+)-Malic acid

CAS 636-61-3HO2CCH2CH(OH)CO2HChemical Synthesis

D-(+)-Malic acid (CAS: 636-61-3), with the molecular formula HO2CCH2CH(OH)CO2H and a molar mass of 134.09 g/mol, is a chiral organic compound. It is widely recognised for its utility as a chiral building block and resolving agent in asymmetric synthesis. This dicarboxylic acid is a crucial intermediate in various chemical synthesis processes, offering a stereochemically defined starting point for complex molecular architectures.

IUPAC
(R)-(+)-2-Hydroxysuccinic acid,D-Hydroxybutanedioic acid
Synonyms
(R)-(+)-2-Hydroxysuccinic acidD-Hydroxybutanedioic acid
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D-(+)-Malic acid (HO2CCH2CH(OH)CO2H) — chemical structure, CAS 636-61-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisCarboxylic AcidsChemical SynthesisChiral Building BlocksChiral Resolution ReagentsChiral Resolving Reagents
01 /Applications

Chiral Building Block in Asymmetric Synthesis

D-(+)-Malic acid serves as a valuable chiral building block, enabling the stereoselective construction of complex molecules. Its defined stereochemistry facilitates its incorporation into synthetic pathways requiring precise spatial arrangement of atoms.

Chiral Resolution Agent

This compound is employed as a chiral resolving agent for the separation of enantiomers. Its ability to form diastereomeric salts or complexes allows for the resolution of racemic mixtures, yielding enantiomerically pure compounds.

Intermediate in Chemical Synthesis

As a versatile dicarboxylic acid, D-(+)-Malic acid finds application as an intermediate in the synthesis of various organic compounds. It is a useful precursor in academic research and industrial chemical production.

02 /Properties
Molecular weight134.09
Linear formulaHO2CCH2CH(OH)CO2H
Assay≥97.0% (T)
Optical activity[α]20/D +28.0±2°, c = 5.5% in pyridine
Melting point98-102 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)37/38-41
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
636-61-3
MDL number
MFCD00004245
Beilstein registry
1723540
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is D-(+)-Malic acid used for?

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D-(+)-Malic acid is primarily used as a chiral building block and chiral resolving agent in asymmetric synthesis and general chemical synthesis.

What is the CAS number and formula for D-(+)-Malic acid?

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The CAS number is 636-61-3 and the molecular formula is HO2CCH2CH(OH)CO2H.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies D-(+)-Malic acid with an assay of ≥97.0% (T). We do not represent this product as USP, BP, or EP grade.

How should D-(+)-Malic acid be handled safely?

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D-(+)-Malic acid is classified as a danger with hazards including skin irritation (H315), serious eye damage (H318), and respiratory irritation (H335). It requires handling with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure good ventilation.

Is D-(+)-Malic acid available for export?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including D-(+)-Malic acid.

How can I request a quote or sample?

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Please contact the Tech Serve Solutions sales team via our website or direct contact details to request a quote or sample of D-(+)-Malic acid.

Need D-(+)-Malic acid in a specific grade or volume?