[D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P
[D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P (CAS: 96736-12-8) is a synthetic peptide analogue of Substance P, designed as a potent antagonist. With a molecular weight of 1516.83 g/mol and the empirical formula C79H109N19O12, this compound plays a crucial role in neuroscientific research. It is primarily utilised for its ability to block tachykinin receptor activity, making it valuable in studies related to cell signaling, neurotransmission, and obesity research.
- IUPAC
- D-Arg-Pro-Lys-Pro-D-Phe-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2,Antagonist D
- Synonyms
- 9, Leu11]-Substance P96736-12-8C79H109N19O12
![[D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P (D-Trp7) — chemical structure, CAS 96736-12-8; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F96736-12-8.png&w=3840&q=75)
Neuroscience Research
This peptide serves as a vital tool in understanding the roles of tachykinins and their receptors in the central and peripheral nervous systems. Its antagonist properties are instrumental in dissecting signaling pathways related to pain, inflammation, and mood.
Obesity Studies
As an antagonist in neurotransmission pathways linked to appetite and metabolism, [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P is employed in research investigating the neurobiological underpinnings of obesity.
Cell Biology
Utilised in cell-based assays to investigate cellular responses mediated by tachykinin receptors. It helps researchers understand receptor-ligand interactions and downstream cellular events.
| Molecular weight | 1516.83 |
|---|---|
| Empirical formula | C79H109N19O12 |
| Assay | ≥95% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... TAC1(6863), TACR1(6869)mouse ... TAC1(21333), TACR1(21336)rat ... TAC1(24806), TACR1(24807) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P used for?
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[D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P is used as an antagonist in neuroscience research, particularly in studies concerning cell signaling, neurotransmission, and obesity, by blocking tachykinin receptor activity.
What are the CAS number and formula for [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P?
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The CAS number is 96736-12-8 and the empirical formula is C79H109N19O12.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at ≥95% purity as determined by HPLC. This product is intended for research use only and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at -20°C. The product carries a WGK Germany rating of 3, indicating it is hazardous.
Is this chemical hazardous?
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Yes, this chemical has a WGK Germany rating of 3, indicating it is hazardous. Appropriate personal protective equipment, including eyeshields, gloves, and potentially a respirator filter, should be used.
How is [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P packed and shipped?
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Tech Serve Solutions expertly packs and ships fine chemicals globally, adhering to all relevant regulations for safe transport.
How can I request a sample or quote?
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To request a sample or quote for [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P, please contact our sales team via the website or by phone.
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