Cyclic Pifithrin-α hydrobromide

CAS 511296-88-1C16H16N2S · HBrCell Biology

Cyclic Pifithrin-α hydrobromide (CAS: 511296-88-1; C16H16N2S · HBr; MW: 349.29) is a chemical compound supplied by Tech Serve Solutions. This molecule functions as a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription. It is valuable in research settings for studying cellular processes, particularly those involving the p53 pathway and programmed cell death. Cyclic Pifithrin-α hydrobromide is typically used in laboratory research applications.

IUPAC: 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide,Cyclic PFT-α hydrobromide,Pifithrin-α, cyclic,QB102
Synonyms: 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromideCyclic PFT-α hydrobromidePifithrin-α, cyclicQB102

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Cyclic Pifithrin-α hydrobromide (C16H16N2S · HBr) — chemical structure, CAS 511296-88-1; Life Science, fine chemical supplied by Tech Serve Solutions

Apoptosis InhibitorsApoptosis and Cell CycleBioactive Small MoleculesCI-CYCell BiologyEnzymesSubstratesInhibitors &General Stem Cell BiologyInhibitors

01 /Applications

Apoptosis Research

Cyclic Pifithrin-α hydrobromide serves as a key reagent for investigating the mechanisms of apoptosis. Its ability to reversibly inhibit p53-mediated cell death makes it useful for studying the role of p53 in cellular regulation and disease.

Gene Transcription Studies

This compound is employed to explore p53-dependent gene transcription. Researchers can utilise Cyclic Pifithrin-α hydrobromide to modulate and study the transcriptional activity controlled by the p53 tumour suppressor protein.

Cellular Signaling Pathways

As a modulator of critical cellular pathways, Cyclic Pifithrin-α hydrobromide is a valuable tool for understanding cellular signalling, particularly in contexts related to cell cycle control and stress responses.

02 /Properties

Molecular weight	349.29
Empirical formula	C16H16N2S · HBr
Assay	≥98% (HPLC)
Solubility	DMSO: soluble20 mg/mL
Storage temperature	−20°C
Application	Reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

511296-88-1

MDL number

MFCD02683960

PubChem substance

24898515

05 /Additional specifications

Shipped In	dry ice

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Cyclic Pifithrin-α hydrobromide used for?

Cyclic Pifithrin-α hydrobromide is used as a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription in laboratory research.

What is the CAS number and chemical formula for Cyclic Pifithrin-α hydrobromide?

The CAS number is 511296-88-1, and the chemical formula is C16H16N2S · HBr.

What grade and purity does Tech Serve Solutions supply for Cyclic Pifithrin-α hydrobromide?

Tech Serve Solutions supplies Cyclic Pifithrin-α hydrobromide with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the safety and handling recommendations for Cyclic Pifithrin-α hydrobromide?

Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The product is classified under WGK 2 in Germany. Always consult the Safety Data Sheet before use.