3-Aminobenzonitrile
3-Aminobenzonitrile (CAS: 2237-30-1), a white to off-white crystalline solid with the formula H2NC6H4CN and a molecular weight of 118.14 g/mol, is a key organic building block. It is primarily utilised in chemical synthesis for the creation of complex heterocyclic compounds. Its nitrile and amine functionalities make it a versatile intermediate in the development of novel pharmaceutical agents and other fine chemicals. Tech Serve Solutions supplies this compound with a high assay of 99%.
- IUPAC
- 3-Cyanoaniline
- Synonyms
- 3-Cyanoaniline
Synthesis of Pyrazole Derivatives
3-Aminobenzonitrile serves as a crucial precursor in the synthesis of various substituted pyrazoles, such as 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles. These compounds are investigated for potential biological activities.
Preparation of Lactam Analogues
This chemical intermediate is employed in the preparation of highly substituted γ-lactam analogues. These analogues are studied as potential therapeutic agents, including those acting as follicle stimulating hormone receptor agonists.
Fine Chemical Synthesis
As a versatile building block, 3-Aminobenzonitrile is used in broader organic synthesis pathways. Its dual amine and nitrile functional groups allow for diverse chemical transformations in the development of novel molecules.
| Molecular weight | 118.14 |
|---|---|
| Linear formula | H2NC6H4CN |
| Assay | 99% |
| Application | 3-Aminobenzonitrile was used in the synthesis of series of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles1. It was also used in the preparation of highly substituted γ-lactam analogues of a thiazolidinone follicle stimulating hormone receptor agonist2. |
| Melting point | 48-53 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H317May cause an allergic skin reaction
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Aminobenzonitrile used for?
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3-Aminobenzonitrile is used as a building block in chemical synthesis, notably for the preparation of pyrazole derivatives and lactam analogues with potential pharmaceutical applications.
What is the CAS number and formula for 3-Aminobenzonitrile?
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The CAS number for 3-Aminobenzonitrile is 2237-30-1, and its molecular formula is H2NC6H4CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Aminobenzonitrile with a minimum assay of 99%. This product is suitable for research and chemical synthesis, and TSS does not represent it as USP, BP, or EP grade.
How should 3-Aminobenzonitrile be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid breathing dust. It is classified with GHS07 symbol and a 'Warning' signal word, with hazard statements H302, H312, H317, and H332.
Is 3-Aminobenzonitrile exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Aminobenzonitrile.
How can I request a sample or quote for 3-Aminobenzonitrile?
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To request a sample or a quote for 3-Aminobenzonitrile, please contact the TSS sales department through our website or by calling our direct line.
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