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Boc-Ala-OH

CAS 15761-38-3CH3CH[NHCO2C(CH3)3]CO2HCatalysis & Inorganic

Boc-Ala-OH (CAS: 15761-38-3), also known as N-(tert-Butoxycarbonyl)-L-alanine, is a crucial protected amino acid derivative. With a molecular weight of 189.21 g/mol, it serves as a fundamental building block in peptide synthesis and organic chemistry. Its tert-butoxycarbonyl (Boc) protecting group allows for controlled peptide chain elongation by selectively masking the amino group. Boc-Ala-OH is widely employed in the development of pharmaceuticals and in biochemical research.

IUPAC
N-(tert-Butoxycarbonyl)-L-alanine,Boc-L-alanine
Synonyms
N-(tert-Butoxycarbonyl)-L-alanineBoc-L-alanine
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Boc-Ala-OH (CH3CH[NHCO2C(CH3)3]CO2H) — chemical structure, CAS 15761-38-3; Chemistry, fine chemical supplied by Tech Serve Solutions
AlanineAmino Acid DerivativesC-H ActivationChemical BiologyChemical SynthesisLigands and AuxiliariesPeptide Chemistry
01 /Applications

Peptide Synthesis

Boc-Ala-OH is a standard Boc-protected amino acid used in solid-phase and solution-phase peptide synthesis. The Boc group facilitates selective coupling reactions, enabling the construction of complex peptide sequences.

Pharmaceutical Intermediates

As a key chiral building block, it is utilised in the synthesis of various pharmaceutical agents and active pharmaceutical ingredients (APIs). Its incorporation is vital for developing novel therapeutic compounds.

Organic Synthesis

This compound finds application in general organic synthesis as a protected alanine source for introducing specific structural motifs into target molecules. It is valuable in creating stereochemically defined compounds.

Biochemical Research

Boc-Ala-OH is used in research laboratories for exploring amino acid chemistry, protein structure-function relationships, and developing new biochemical tools.

02 /Properties
Molecular weight189.21
Linear formulaCH3CH[NHCO2C(CH3)3]CO2H
Assay≥99.0% (TLC)
Optical activity[α]20/D −25±1°, c = 2% in acetic acid
Melting point79-83 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
15761-38-3
MDL number
MFCD00037225
Beilstein registry
1726365
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Ala-OH used for?

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Boc-Ala-OH is primarily used as a protected amino acid in peptide synthesis, as a building block for pharmaceutical intermediates, and in broader organic synthesis and biochemical research.

What are the CAS number and formula for Boc-Ala-OH?

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The CAS number for Boc-Ala-OH is 15761-38-3, and its linear formula is CH3CH[NHCO2C(CH3)3]CO2H.

What grade and purity does Tech Serve Solutions supply for Boc-Ala-OH?

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Tech Serve Solutions supplies Boc-Ala-OH with an assay of ≥99.0% (TLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Boc-Ala-OH be handled safely?

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When handling Boc-Ala-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the Safety Data Sheet for detailed guidance.

How is Boc-Ala-OH shipped and exported?

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Tech Serve Solutions, as a specialist global supplier and exporter, carefully packs and ships Boc-Ala-OH to meet international shipping regulations and customer requirements.

How can I request a sample or quote for Boc-Ala-OH?

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To request a sample or a quotation for Boc-Ala-OH, please contact our sales team through the website or via direct inquiry, providing your specific requirements.

Need Boc-Ala-OH in a specific grade or volume?