Cyclic adenosine diphosphate-ribose
Cyclic adenosine diphosphate-ribose (cADPR), CAS 119340-53-3, with the molecular formula C15H21N5O13P2, is a key intracellular second messenger. It plays a vital role in regulating intracellular calcium release via ryanodine receptors. This compound is crucial for processes such as glucose-induced insulin release in the pancreas and abscisic acid-mediated calcium signalling in plants. Supplied by Tech Serve Solutions as a lyophilised powder.
- IUPAC
- ADP-cyclo[N1:1′′]-ribose,Cyclic ADPR,cADP-ribose,cADPR
Intracellular Calcium Signalling
cADPR mobilises intracellular Ca2+ from storage sites like the sarcoplasmic reticulum, primarily by activating ryanodine receptors. This mechanism is fundamental to numerous cellular processes.
Endocrine Pancreas Function
It acts as a second messenger in the regulation of glucose-stimulated insulin secretion from pancreatic endocrine cells, contributing to glucose homeostasis.
Plant Physiology
In plants, cADPR is involved in signalling pathways, notably mediating calcium release in response to plant hormones such as abscisic acid.
Neuroscience Research
As a cell signalling molecule influencing calcium dynamics, cADPR has relevance in understanding neuronal function and neurological processes.
| Empirical formula | C15H21N5O13P2 |
|---|---|
| Assay | ≥90% (HPLC) |
| Form | lyophilized powder |
| Storage temperature | −20°C |
| Application | Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclic adenosine diphosphate-ribose used for?
+
Cyclic adenosine diphosphate-ribose (cADPR) is used as an intracellular second messenger to mobilise intracellular calcium stores, playing roles in insulin release and plant signalling.
What is the CAS number and molecular formula for Cyclic adenosine diphosphate-ribose?
+
The CAS number is 119340-53-3 and the molecular formula is C15H21N5O13P2.
What grade and purity does Tech Serve Solutions supply for Cyclic adenosine diphosphate-ribose?
+
Tech Serve Solutions supplies Cyclic adenosine diphosphate-ribose with a purity of ≥90% (HPLC), as a lyophilised powder. This is suitable for research applications. We do not represent this product as USP, BP, EP or pharmaceutical grade.
How should Cyclic adenosine diphosphate-ribose be handled and stored?
+
Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Store at -20°C. Hazards include skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is Cyclic adenosine diphosphate-ribose a controlled substance?
+
The provided data does not indicate that Cyclic adenosine diphosphate-ribose is a controlled substance.
How are products like Cyclic adenosine diphosphate-ribose packed, shipped, and exported by TSS?
+
Tech Serve Solutions specialises in the global export of fine chemicals, ensuring appropriate packaging and adherence to international shipping regulations for hazardous materials.
How can I request a sample or quote for Cyclic adenosine diphosphate-ribose?
+
Please contact our sales team directly through the website or by phone to request a sample or a formal quotation for Cyclic adenosine diphosphate-ribose.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis