α-Cyano-4-hydroxycinnamic acid N-tert-butyl-N-isopropyl-N-methylammonium salt
α-Cyano-4-hydroxycinnamic acid N-tert-butyl-N-isopropyl-N-methylammonium salt (CAS: 1194607-11-8) is a second-generation ionic liquid matrix (ILM) designed for Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry (MALDI-MS). Its advanced formulation makes it particularly suitable for the analysis of peptides and proteins within a broad molecular weight range of 1,000 to 270,000 Da. This compound is a key reagent for researchers in proteomics and molecular biology.
- IUPAC
- N-tert-Butyl-N-isopropyl-N-methylammonium α-cyano-4-hydroxycinnamate,IMTBA α-CHCA
- Synonyms
- N-tert-Butyl-N-isopropyl-N-methylammonium α-cyano-4-hydroxycinnamateIMTBA α-CHCA

MALDI-MS Matrix for Peptides and Proteins
Utilised as an ionic liquid matrix (ILM) for MALDI-MS, this compound excels in the ionisation and detection of peptides and proteins. It is effective for analytes ranging from 1,000 to 270,000 Da, offering reliable performance in mass spectrometry applications.
Proteomics and Molecular Biology Research
This matrix substance is an essential tool for researchers in proteomics and molecular biology. Its specific properties facilitate accurate mass analysis, aiding in the identification and characterisation of biological molecules.
Analytical and Chromatography
As a high-purity analytical reagent, it finds applications in various chromatographic techniques and mass spectrometry-based analyses. Its consistent performance supports precise analytical outcomes.
| Empirical formula | C10H7NO3 · C8H19N |
|---|---|
| Assay | ≥99.0% (HPLC) |
| Grade | matrix substance for MALDI-MS |
| Storage temperature | 2-8°C |
| Application | Second generation ionic liquid matrix (ILM) for MALDI-MS, suitable for peptides and proteins from 1,000 to 270,000 Da. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T,N |
| Risk statements (R) | 22-36/37/38-52/53 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | ELITE |
|---|---|
| Analyte Suitability | peptidesproteins |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Cyano-4-hydroxycinnamic acid N-tert-butyl-N-isopropyl-N-methylammonium salt used for?
+
This compound is primarily used as a second-generation ionic liquid matrix (ILM) for MALDI-MS, particularly effective for analysing peptides and proteins within the 1,000 to 270,000 Da range.
What are the CAS number and formula?
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The CAS number is 1194607-11-8 and the empirical formula (Hill notation) is C10H7NO3 · C8H19N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a matrix substance for MALDI-MS with a purity of ≥99.0% (HPLC), meeting the ELITE quality level. It is not represented as USP, BP, or EP grade.
How should this chemical be handled and stored?
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This compound is classified as a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335), with long-term harmful effects to aquatic life (H412). Store at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quote or sample for α-Cyano-4-hydroxycinnamic acid N-tert-butyl-N-isopropyl-N-methylammonium salt.
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