α-Cyano-4-fluorocinnamic acid
α-Cyano-4-fluorocinnamic acid (CAS: 118409-66-8) is an organic compound with the chemical formula C10H6FNO2 and a molecular weight of 191.16 g/mol. It is primarily utilised as a matrix substance for Matrix-Assisted Laser Desorption/Ionisation (MALDI) mass spectrometry. This application is crucial for the ionisation of various analytes, including peptides, lipids, and pharmaceuticals, enabling their detection and analysis.
- IUPAC
- α-Cyano-p-fluorocinnamic acid,2-Cyano-3-(4-fluorophenyl)-2-propenoic acid,FCCA,NSC 638135
- Synonyms
- α-Cyano-p-fluorocinnamic acid2-Cyano-3-(4-fluorophenyl)-2-propenoic acidFCCANSC 638135
MALDI Mass Spectrometry Matrix
α-Cyano-4-fluorocinnamic acid serves as an effective matrix material for MALDI-MS analysis. Its properties facilitate the efficient transfer of energy to the analyte, promoting ionisation and enabling the analysis of fragile biomolecules and pharmaceuticals.
Analysis of Fragile Analytes
This compound is suitable for the analysis of delicate analytes such as peptides, phospholipids, and drugs. It is also recommended for techniques like CID-MS/MS and ME-SIMS, offering versatility in mass spectrometry applications.
Lipid and Peptide Analysis
It is employed in the precise quantification and analysis of various lipids, including chlorinated lipids and phospholipids, as well as peptides and phosphopeptides. Its utility extends to the analysis of ionic liquids.
| Molecular weight | 191.16 |
|---|---|
| Empirical formula | C10H6FNO2 |
| Assay | ≥95.0% (HPLC) |
| Grade | matrix substance for MALDI-MS |
| Solubility | methanol: soluble100 mg/10 mL, clear, colorless to light yellow |
| Application | suitable as MALDI-Matrix material |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36-37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Analyte Suitability | CID-MS/MSME-SIMSchlorinated lipidsdrugsfragile analytesionic liquids (quantification)lipidspeptidesphospholipidsphosphopeptides |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Cyano-4-fluorocinnamic acid used for?
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α-Cyano-4-fluorocinnamic acid is primarily used as a matrix substance for MALDI-MS (Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry), particularly for the analysis of fragile analytes like peptides, lipids, and pharmaceuticals.
What is the CAS number and chemical formula?
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The CAS number is 118409-66-8 and the chemical formula is C10H6FNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies α-Cyano-4-fluorocinnamic acid with an assay of ≥95.0% (HPLC), specified as a matrix substance for MALDI-MS. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should α-Cyano-4-fluorocinnamic acid be handled?
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Handling requires caution. It is a warning substance that may cause skin, eye, and respiratory irritation (H315, H319, H335). It is also harmful if swallowed, inhaled, or in contact with skin (H302 + H312 + H332). Ensure adequate ventilation and wear appropriate personal protective equipment (P261, P280, P305 + P351 + P338).
Is this chemical a controlled substance?
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The provided data does not indicate that α-Cyano-4-fluorocinnamic acid is a controlled substance.
How can I request a quote or sample?
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To request a quote or a sample of α-Cyano-4-fluorocinnamic acid, please contact our sales team through the website or by phone. We are a global supplier and exporter, ready to assist with your requirements.
How is this chemical packed and shipped?
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This product is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations for chemical compounds.
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