Cromakalim
Cromakalim (CAS 94470-67-4), with the molecular formula C16H18N2O3 and a molecular weight of 286.33 g/mol, is a bioactive small molecule. It functions as a potassium channel opener, with key applications in cell biology and neuroscience research. This compound is essential for investigating ion channel activity and cellular signalling pathways, particularly those involving voltage-gated potassium channels.
- IUPAC
- (±)-trans-6-Cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-1-benzopyran-3-ol

Ion Channel Research
Cromakalim is widely utilised to study the function and modulation of potassium channels. It serves as a valuable tool for researchers investigating cellular excitability and ion transport mechanisms.
Cell Signaling Studies
As a modulator of ion channels, Cromakalim plays a role in understanding complex cell signalling cascades. Its effects are crucial for research in neuroscience and cardiovascular physiology.
Neuroscience Investigations
This compound is employed in neuroscience to explore the role of potassium channels in neuronal function and synaptic transmission. It aids in characterising the physiological impact of ion channel modulation.
| Molecular weight | 286.33 |
|---|---|
| Empirical formula | C16H18N2O3 |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Kcna1(24520), Kcnj1(24521), Kcnj5(29713), Kcnj8(25472) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cromakalim used for?
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Cromakalim is used in scientific research for investigating ion channels, particularly potassium channels, and for studying cell signaling pathways in neuroscience and related fields.
What is the CAS number and formula for Cromakalim?
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The CAS number for Cromakalim is 94470-67-4, and its molecular formula is C16H18N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cromakalim as a research-grade chemical with high purity. We do not represent this product as USP, BP, or EP grade.
How should Cromakalim be handled and stored?
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Handle Cromakalim with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 or P1 respirator. Store at 2-8°C. It is classified under WGK Germany 3, indicating a hazard to water.
Is Cromakalim a controlled substance?
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The provided data does not indicate that Cromakalim is a controlled substance.
How are your chemicals packed and shipped?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all necessary regulations for safe export.
How can I request a sample or quote for Cromakalim?
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To request a sample or quote for Cromakalim, please contact our sales team through the website or your dedicated account manager.
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