Clonidine hydrochloride
Clonidine hydrochloride (CAS: 4205-91-8), with the molecular formula C9H9Cl2N3 · HCl and a molecular weight of 266.55, is a potent alpha-adrenergic agonist. This compound is primarily utilised in scientific research for its pharmacological effects. It is a valuable reagent in studies related to cardiovascular function, pain management, and neurological research due to its mechanism of action.
- IUPAC
- 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

Pharmacological Research
Used as a tool compound in preclinical research to investigate alpha-adrenergic receptor pathways and their role in various physiological processes. Its effects on blood pressure and sedation are subjects of study.
Neuroscience Studies
Investigated for its potential effects on neurotransmitter systems and its applications in understanding conditions affecting the central nervous system. It serves as a reference compound in receptor binding assays.
Cardiovascular Research
Employed in studies examining its impact on blood pressure regulation and its mechanisms of action within the cardiovascular system. It is used to model hypotensive effects in experimental settings.
| Molecular weight | 266.55 |
|---|---|
| Empirical formula | C9H9Cl2N3 · HCl |
| Solubility | H2O: solublemethanol: soluble |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811PIH 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 25-26 |
| Safety statements (S) | 22-26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Clonidine hydrochloride used for?
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Clonidine hydrochloride (CAS: 4205-91-8) is primarily used in scientific and pharmacological research to study alpha-adrenergic receptor function, cardiovascular regulation, and neurological pathways. It is a valuable tool compound for preclinical investigations.
What are the CAS number and formula for Clonidine hydrochloride?
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The CAS number for Clonidine hydrochloride is 4205-91-8, and its empirical formula is C9H9Cl2N3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Clonidine hydrochloride as a research-grade chemical. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as meeting pharmacopoeial standards such as USP, BP, or EP unless explicitly stated.
How should Clonidine hydrochloride be handled safely?
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Clonidine hydrochloride is classified as acutely toxic (H301, H330) and requires careful handling. Always use appropriate personal protective equipment, including eyeshields, gloves, and a respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is Clonidine hydrochloride a controlled substance?
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While Clonidine hydrochloride is a prescription medication in many regions, its status as a controlled substance for research purposes can vary by jurisdiction. Customers should verify local regulations concerning its possession and use.
How is Clonidine hydrochloride packed and shipped?
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Clonidine hydrochloride is carefully packed in accordance with international shipping regulations for hazardous materials. We export globally to research institutions and qualified businesses. For specific packaging and shipping details, please contact our sales team.
How can I request a sample or quote for Clonidine hydrochloride?
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To request a sample or a quotation for Clonidine hydrochloride, please visit our website or contact our customer service department directly with your inquiry, including the product name and CAS number.
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