Clobetasone butyrate
Clobetasone butyrate (CAS 25122-57-0) is a halogenated corticosteroid with the empirical formula C26H32ClFO5 and a molecular weight of 478.98. It is a synthetic compound primarily utilised in dermatological applications for its anti-inflammatory properties. Available from Tech Serve Solutions with an assay of ≥98%, it serves as a research chemical for investigations into steroid-based therapies and related biological pathways.
- IUPAC
- 21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-butyrate

Dermatological Research
Clobetasone butyrate is investigated for its potent anti-inflammatory and immunosuppressive activities, relevant to the development of topical treatments for various skin conditions. Its mechanism involves modulating inflammatory mediators and cellular responses in the skin.
Cell Biology Studies
This compound can be employed in cell-based assays to study corticosteroid receptor interactions and downstream signalling pathways. Its use aids in understanding the molecular mechanisms underlying steroid action.
Hematology and Histology Research
As a research reagent, Clobetasone butyrate may be used in studies concerning immune cell function and inflammatory processes within blood and tissue samples. Its effects on cellular morphology and function are areas of investigation.
| Molecular weight | 478.98 |
|---|---|
| Empirical formula | C26H32ClFO5 |
| Assay | ≥98% |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Clobetasone butyrate used for?
+
Clobetasone butyrate is used in research settings, particularly in dermatological and cell biology studies, to investigate its anti-inflammatory and immunosuppressive properties. It is not for medicinal use.
What is the CAS number and chemical formula for Clobetasone butyrate?
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The CAS number for Clobetasone butyrate is 25122-57-0, and its empirical formula is C26H32ClFO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Clobetasone butyrate with an assay of ≥98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Clobetasone butyrate be handled safely?
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Handle Clobetasone butyrate with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a respirator (type N100 or P3 filter) if exposure is likely, as it is suspected of causing cancer (H351).
How is Clobetasone butyrate packed and shipped?
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Clobetasone butyrate is carefully packed to ensure integrity during transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for Clobetasone butyrate?
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To request a sample or a quote for Clobetasone butyrate, please contact our sales team through the website or by phone, providing your specific requirements.
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