cis-Cyclobutane-1,2-dicarboxylic acid
cis-Cyclobutane-1,2-dicarboxylic acid (CAS: 1461-94-5) is a cyclic organic compound with the molecular formula C6H8O4 and a molecular weight of 144.13 g/mol. This building block is characterised by its cis configuration within the cyclobutane ring. It serves as a key intermediate in organic synthesis, particularly in the development of novel chemical entities and functional materials, finding utility across various research and development sectors.
- Synonyms
- C6H8O4cyclobutane-1,2-dicarboxylic acid, cis-

Organic Synthesis Intermediate
Used as a precursor in the synthesis of more complex organic molecules, leveraging its dicarboxylic acid functionality and cyclobutane core. It is valuable for constructing specific molecular architectures in medicinal chemistry and materials science research.
Chemical Research and Development
Employed in academic and industrial laboratories for fundamental chemical research and the exploration of new synthetic routes. Its unique structure makes it a useful component for structure-activity relationship studies.
Materials Science
Incorporated into the development of novel polymers and functional materials where the cyclobutane ring can impart specific thermal or mechanical properties. Its difunctional nature allows for polymer chain extension or cross-linking.
| Molecular weight | 144.13 |
|---|---|
| Empirical formula | C6H8O4 |
| Assay | ≥97.0% (T) |
| Melting point | 133-139 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is cis-Cyclobutane-1,2-dicarboxylic acid used for?
+
cis-Cyclobutane-1,2-dicarboxylic acid is primarily used as a building block and intermediate in organic synthesis, particularly in research and development for creating complex molecules and novel materials.
What is the CAS number and formula for cis-Cyclobutane-1,2-dicarboxylic acid?
+
The CAS number is 1461-94-5, and its molecular formula is C6H8O4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies cis-Cyclobutane-1,2-dicarboxylic acid with an assay of ≥97.0% (T). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should cis-Cyclobutane-1,2-dicarboxylic acid be handled safely?
+
This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and follow all safety precautions.
Is cis-Cyclobutane-1,2-dicarboxylic acid a controlled substance?
+
The provided data does not indicate that cis-Cyclobutane-1,2-dicarboxylic acid is a controlled substance.
How is this chemical shipped or exported?
+
This chemical is classified under UN 3261, 8 / PGIII for transport. Tech Serve Solutions adheres to all relevant regulations for safe shipping and export.
How can I request a sample or quote?
+
To request a sample or a quote for cis-Cyclobutane-1,2-dicarboxylic acid, please contact our sales team through the website or by phone.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis