CGP 37849
CGP 37849 (CAS: 127910-31-0), a white to beige powder with the empirical formula C6H12NO5P and a molecular weight of 209.14 g/mol, is a valuable research chemical. Its primary application lies in the study of NMDA receptor-mediated cell signalling pathways within neuroscience and cell biology research. This compound is supplied with an assay of ≥98% (HPLC) for demanding scientific applications.
- IUPAC
- (3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid

NMDA Receptor Research
CGP 37849 serves as a potent NMDA antagonist, making it an indispensable tool for researchers investigating the role of NMDA receptors in various physiological and pathological processes. Its application aids in understanding excitotoxicity, synaptic plasticity, and neurological disorders.
Cell Signalling Studies
This compound is utilized to probe NMDA-mediated cell signalling cascades. By blocking NMDA receptor activity, researchers can elucidate downstream signalling events and their impact on cellular function and survival in the central nervous system.
Neurotransmission Investigations
CGP 37849 is employed in studies focused on excitatory amino acid neurotransmission. It helps researchers dissect the complex mechanisms of neurotransmitter release, receptor binding, and signal transduction in neuronal circuits.
| Molecular weight | 209.14 |
|---|---|
| Empirical formula | C6H12NO5P |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: ≥2 mg/mL (warmed) |
| Storage temperature | 2-8°C |
| Application | CGP 37849 may be used in NMDA-mediated cell signaling studies. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CGP 37849 used for?
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CGP 37849 is primarily used for research into NMDA receptor-mediated cell signalling, neuroscience, and neurotransmission studies. It acts as an NMDA antagonist.
What is the CAS number and chemical formula for CGP 37849?
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The CAS number for CGP 37849 is 127910-31-0, and its empirical formula is C6H12NO5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies CGP 37849 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should CGP 37849 be handled and stored?
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CGP 37849 is classified as a warning substance (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Store desiccated at 2-8°C.
Is CGP 37849 a controlled substance?
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Based on the provided data, CGP 37849 is not indicated as a controlled substance. However, regulations can vary by jurisdiction.
How is CGP 37849 packed and exported?
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CGP 37849 is typically supplied as a powder in sealed containers, suitable for safe handling and international export according to chemical shipping regulations.
How can I request a quote or sample of CGP 37849?
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To request a quote or a sample of CGP 37849, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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