CD437
CD437 (CAS: 125316-60-1), with the molecular formula C27H26O3 and a molecular weight of 398.49 g/mol, is a yellow solid compound. It functions as a potent apoptosis inducer, playing a critical role in cellular programmed death pathways. This compound is a valuable tool in biological research, particularly for studies involving cell cycle regulation, gene expression, and signal transduction.
- IUPAC
- 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid,AHPN
- Synonyms
- 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid,AHPN

Apoptosis Research
CD437 is widely employed as an apoptosis inducer in various research settings. It facilitates the study of programmed cell death mechanisms, making it instrumental in understanding cellular fate and disease pathology.
Cell Cycle Regulation Studies
This compound aids in investigating the intricate processes that govern the cell cycle. Researchers utilise CD437 to explore how external factors and molecular signals influence cell division and proliferation.
Gene Expression Analysis
CD437 serves as a tool for examining gene regulation and expression patterns, particularly those related to cell death and differentiation pathways. It helps elucidate the molecular basis of cellular responses.
PPAR and RXR Pathway Modulation
As a regulator of PPAR and RXR pathways, CD437 is used to study their roles in metabolic processes and cellular signalling. This application is relevant for understanding therapeutic targets in metabolic diseases.
| Molecular weight | 398.49 |
|---|---|
| Empirical formula | C27H26O3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | −20°C |
| Melting point | 271.6-276 °C |
| Impurities tested | ~0.5 mol/mol water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... RARA(5914), RARB(5915), RARG(5916) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is CD437 used for?
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CD437 is used in scientific research as an apoptosis inducer, for studying cell cycle regulation, gene expression, and modulation of PPAR and RXR pathways.
What is the CAS number and molecular formula for CD437?
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The CAS number for CD437 is 125316-60-1 and its molecular formula is C27H26O3.
What grade and purity does Tech Serve Solutions supply for CD437?
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Tech Serve Solutions supplies CD437 with an assay of ≥98% (HPLC). This product is not intended for human or veterinary use and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for CD437?
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CD437 (CAS: 125316-60-1) is classified under WGK Germany 3. Handling requires appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Avoid inhalation and skin/eye contact. Store at -20°C.
How is CD437 packaged and shipped?
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CD437 is typically supplied as a yellow solid and stored at -20°C. TSS exports chemicals globally, ensuring proper packaging and documentation for international shipments.
How can I request a quote or sample of CD437?
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To request a quote or sample of CD437, please contact the Tech Serve Solutions sales team through our website or by phone.
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