Cefsulodin sodium salt hydrate

CAS 52152-93-9C22H19N4NaO8S2 · xH2OBiochemicals & Reagents

Cefsulodin sodium salt hydrate (CAS: 52152-93-9), with the empirical formula C22H19N4NaO8S2 · xH2O, is a third-generation cephalosporin antibiotic. It exhibits specific activity against *Pseudomonas aeruginosa*. This compound is utilised in laboratory settings, notably in CIN agar for the selective isolation of microorganisms such as *E. coli*. It also serves as a tool in research to investigate bacterial cell wall synthesis mechanisms and multidrug resistance.

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Cefsulodin sodium salt hydrate (C22H19N4NaO8S2 · xH2O) — chemical structure, CAS 52152-93-9; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Selective Media Component

Cefsulodin sodium salt hydrate is incorporated into CIN (cefsulodin-Irgasan-novobiocin) agar. This selective medium is crucial for the isolation and identification of specific microorganisms, particularly differentiating against Gram-positive bacteria.

Antibacterial Research

Its specific activity against *Pseudomonas aeruginosa* makes it valuable for studying the efficacy and mechanisms of action of cephalosporin antibiotics. This includes research into bacterial cell wall synthesis and the role of penicillin-binding proteins (PBPs).

Drug Efflux Transport Studies

Cefsulodin has been employed as a substrate to investigate the function of multidrug resistance-associated proteins (MRPs) and their role in the transport of various molecules, such as prostaglandin E2, across biological barriers like the blood-brain barrier.

02 /Properties

Molecular weight	554.53 (anhydrous basis)
Empirical formula	C22H19N4NaO8S2 · xH2O
Storage temperature	2-8°C
Application	Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. Cefuslodin is used in CIN (cefsulodin-Irgasan-novobiocin) agar to select for microorganisms such as E. coli. Cefsulodin is a substrate for rat Oatp1a4. It has been used to study multidrug resistance-associated protein 4 in efflux transport of prostaglandin E2 across the mouse blood-brain barrier1. Cefsulodin is used to study the effect of expression, binding, and inhibition of PBP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	2
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38-42/43
Safety statements (S)	22-26-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

52152-93-9

MDL number

MFCD07793338

PubChem substance

24278340

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Cefsulodin sodium salt hydrate primarily used for?

Cefsulodin sodium salt hydrate is primarily used as a selective antibacterial agent in laboratory media, particularly for isolating *Pseudomonas aeruginosa*, and in research for studying bacterial cell wall synthesis and drug transport mechanisms.

What is the CAS number and formula for Cefsulodin sodium salt hydrate?

The CAS number is 52152-93-9, and the empirical formula is C22H19N4NaO8S2 · xH2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Cefsulodin sodium salt hydrate for research and laboratory use. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.

How should Cefsulodin sodium salt hydrate be handled safely?

Handle Cefsulodin sodium salt hydrate with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US). Ensure adequate ventilation, as it may cause respiratory irritation (H335). Avoid contact with skin and eyes (H315, H319) and prevent sensitisation through skin contact (H317).

How is Cefsulodin sodium salt hydrate shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Cefsulodin sodium salt hydrate is carefully packaged according to international shipping regulations and can be exported worldwide.

How can I request a quote or sample?

To request a quote or a sample of Cefsulodin sodium salt hydrate, please visit the Tech Serve Solutions website or contact our sales team directly with your specific requirements.