Ceftazidime hydrate
Ceftazidime hydrate (CAS: 120618-65-7), with the molecular formula C22H22N6O7S2 · xH2O and a molecular weight of 546.58 on an anhydrous basis, is a critical research chemical. It is employed in studies investigating the inhibition of penicillin-binding proteins and their role in bacterial cell wall synthesis. This compound is also utilised in bacterial susceptibility testing and for selecting specific mutant colonies.
- IUPAC
- 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum
Antibacterial Research
Ceftazidime hydrate is used to study the expression, binding, and inhibition of penicillin-binding proteins, particularly PBP3, which are essential for bacterial cell wall mucopeptide synthesis.
Bacterial Susceptibility Testing
This compound serves as a valuable reagent in bacterial susceptibility studies to determine the effectiveness of potential antibacterial agents.
Mutant Colony Selection
It can be applied in microbiological research for the selective isolation and identification of specific mutant bacterial colonies.
| Molecular weight | 546.58 (anhydrous basis) |
|---|---|
| Empirical formula | C22H22N6O7S2 · xH2O |
| Assay | 90.0-105.0% |
| Storage temperature | 2-8°C |
| Contains / stabiliser | 10% sodium carbonate as stabilizer |
| Application | Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies1 and to select mutant colonies of interest.2 |
Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 42/43 |
| Safety statements (S) | 22-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ceftazidime hydrate used for?
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Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.
What are the CAS number and formula for Ceftazidime hydrate?
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The CAS number for Ceftazidime hydrate is 120618-65-7, and its empirical formula is C22H22N6O7S2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ceftazidime hydrate with an assay of 90.0-105.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling Ceftazidime hydrate?
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Ceftazidime hydrate is labelled with GHS08 symbol and a Danger signal word. It carries hazard statements H317, H319, and H334, indicating it may cause an allergic skin reaction, serious eye irritation, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. Appropriate personal protective equipment, including a dust mask (US N95), eyeshields, face shields, and gloves, should be used. Handle in a well-ventilated area.
How is Ceftazidime hydrate packed and shipped?
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Ceftazidime hydrate is typically stored at 2-8°C and contains 10% sodium carbonate as a stabilizer. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of Ceftazidime hydrate, please contact our sales team through the website or call us directly. We will be happy to assist you with your specific requirements.
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