Calycosin

CAS 20575-57-9C16H12O5Cell Biology

Calycosin (CAS: 20575-57-9), with the empirical formula C16H12O5 and a molecular weight of 284.26, is an isoflavone phytoestrogen. It is primarily utilised in scientific research for studying its potential mechanisms in angiogenesis, neuroprotection, and calcium channel blocking activity. Calycosin is also investigated for its role in protecting HUVECs from advanced glycation end products-induced macrophage infiltration, contributing to cell biology and nutrition research.

IUPAC: 3′,7-Dihydroxy-4′-methoxy-isoflavone,Cyclosin
Synonyms: 3′,7-Dihydroxy-4′-methoxy-isoflavone, Cyclosin

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Calycosin (C16H12O5) — chemical structure, CAS 20575-57-9; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyIsoflavonesNutrition Research

01 /Applications

Angiogenesis Research

Calycosin can be employed to investigate its mechanisms of angiogenesis, particularly through interactions with the estrogen receptor and the mitogen-activated protein kinase (MAPK) signaling pathway.

Neuroprotection Studies

This compound may be used to explore its function and role in neuroprotection, including the prevention of reperfusion injury.

Calcium Channel Modulation

Calycosin has been investigated for its potential activity as a calcium channel blocker in various biological systems.

Endothelial Cell Protection

It can be utilised to study its protective effects on HUVECs against damage induced by advanced glycation end products and subsequent macrophage infiltration.

02 /Properties

Molecular weight	284.26
Empirical formula	C16H12O5
Assay	≥98% (HPLC)
Solubility	methanol: soluble1 mg/mL, clear, colorless
Storage temperature	2-8°C
Application	Calycosin, a phytoestrogen isoflavone, may be used to promote and study its mechanisms of angiogenesis via interaction with the estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway. Calycosin may be used to study its function and role in neuroprotection via prevention of reperfusion injury. Calycosin may be used as a calcium channel blocker. Calycosin can be used to study its role in protection of HUVECs from advanced glycation end products-induced macrophage infiltration.

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Transport (UN / ADR)	UN 3462 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

20575-57-9

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Calycosin used for?

Calycosin is used in scientific research to study its mechanisms of angiogenesis, neuroprotection, and as a potential calcium channel blocker. It is also investigated for its role in protecting HUVECs from advanced glycation end products-induced macrophage infiltration.

What is the CAS number and formula for Calycosin?

The CAS number for Calycosin is 20575-57-9, and its empirical formula is C16H12O5.

What grade and purity does Tech Serve Solutions supply for Calycosin?

Tech Serve Solutions supplies Calycosin with a minimum purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Calycosin be handled and stored?

Calycosin is classified with GHS06 symbol and a Danger signal word, with hazard statement H301. Handle with extreme care. It is recommended to store Calycosin at 2-8°C.

Is Calycosin a controlled substance?

Based on the provided data, Calycosin has a hazard classification of T (Toxic) in Europe (hazard code 25) and is classified under UN 3462 6.1 / PGIII. It is not explicitly listed as a controlled substance in this documentation.

How is Calycosin shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Calycosin is shipped and exported in accordance with international regulations for hazardous materials, such as UN 3462 6.1 / PGIII.