Calpeptin

CAS 117591-20-5C20H30N2O4Cell Biology

Calpeptin (CAS: 117591-20-5; C20H30N2O4) is a white to beige powder with a molecular weight of 362.46 g/mol. This compound serves as a potent calpain inhibitor, crucial for research into apoptosis and cellular signaling pathways. It is primarily utilised in biochemical and cell biology studies to investigate the roles of calpain proteases in various physiological and pathological processes. Calpeptin is a valuable reagent for researchers exploring neurodegenerative diseases and other conditions involving programmed cell death.

IUPAC: N-Benzyloxycarbonyl-L-leucylnorieucinal,Z-Leu-Nle-CHO
Synonyms: N-Benzyloxycarbonyl-L-leucylnorieucinalZ-Leu-Nle-CHO

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Calpeptin (C20H30N2O4) — chemical structure, CAS 117591-20-5; Life Science, fine chemical supplied by Tech Serve Solutions

Apoptosis InhibitorsApoptosis and Cell CycleCalpain ICell BiologyEnzyme InhibitorsPeptides and Proteins

01 /Applications

Calpain Inhibition Research

Calpeptin is widely used as a selective inhibitor of calpain proteases. This application is vital for studying the involvement of calpains in cellular processes such as apoptosis, cell proliferation, and signal transduction in various biological systems.

Apoptosis and Cell Cycle Studies

As an apoptosis inhibitor, Calpeptin is instrumental in experimental models investigating programmed cell death and its regulation. Researchers employ it to modulate calpain activity, thereby influencing cell cycle progression and survival.

Neuroscience Research

Calpeptin aids in the study of neurological conditions where calpain dysregulation is implicated. Its use helps elucidate the role of these proteases in neuronal function, cell damage, and potential therapeutic targets in neurodegenerative disorders.

Cell Signaling Investigations

This compound is employed to dissect complex cell signaling cascades. By inhibiting calpains, researchers can better understand their downstream effects on various cellular pathways and responses.

02 /Properties

Molecular weight	362.46
Empirical formula	C20H30N2O4
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble15 mg/mL, clear
Storage temperature	−20°C

03 /Identifiers & registry

CAS number

117591-20-5

04 /Additional specifications

Shipped In	wet ice

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Calpeptin used for?

Calpeptin is used as a selective calpain inhibitor in research for studying apoptosis, cell cycle regulation, cell signaling, and neuroscience. It helps researchers investigate the physiological and pathological roles of calpain proteases.

What is the CAS number and molecular formula for Calpeptin?

The CAS number for Calpeptin is 117591-20-5, and its molecular formula is C20H30N2O4.

What grade and purity does Tech Serve Solutions supply for Calpeptin?

Tech Serve Solutions supplies Calpeptin with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.

How should Calpeptin be handled and stored?

Calpeptin is classified with a WGK Germany of 3, indicating it is hazardous. It should be handled with appropriate personal protective equipment in a well-ventilated area. Store at -20°C as supplied.

How is Calpeptin shipped?

Calpeptin is shipped on wet ice to maintain its stability during transit. It is exported globally by Tech Serve Solutions.

How can I request a quote or sample for Calpeptin?

To request a quote or sample of Calpeptin, please contact our sales team through the website or via direct email, providing your specific requirements and shipping details.