Caged MK801
Caged MK801 (CAS: 217176-91-5, Formula: C26H24N2O6) is a potent NMDA receptor antagonist and a derivative of Dizocilpine. Supplied as a white to light yellow powder with a purity of ≥98% (HPLC), this compound is primarily utilized in neuroscientific research for investigating NMDA receptor function and related cellular pathways. Its caged nature allows for controlled release of the active MK801 moiety, making it a valuable tool for temporal studies in cell biology and neuroscience.
- IUPAC
- 10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester,Dizocilpine N-(4,5-dimethoxy-2-nitrobenzyl) carbamate,cMK801
- Synonyms
- cMK801Dizocilpine N-(4,5-dimethoxy-2-nitrobenzyl) carbamate10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
Neuroscience Research Tool
Caged MK801 serves as a crucial research tool in neuroscience for the study of NMDA receptor-gated ion channels. Its caged structure enables precise temporal control over receptor activation, facilitating detailed investigations into neuronal signaling and excitotoxicity.
Cell Biology Studies
This compound is employed in cell biology to explore the role of NMDA receptors in various cellular processes. Researchers use it to understand the downstream effects of NMDA receptor activation in neuronal cells, contributing to a deeper understanding of neurological function and dysfunction.
Ligand-Gated Ion Channel Modulation
As a modulator of ligand-gated ion channels, Caged MK801 is instrumental in research focused on excitatory amino acid neurotransmission. It aids in elucidating the complex mechanisms governing synaptic plasticity and neuronal excitability.
| Empirical formula | C26H24N2O6 |
|---|---|
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to light yellow |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | protect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Caged MK801 primarily used for?
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Caged MK801 is primarily used as a research tool in neuroscience and cell biology to study the function of NMDA receptors and their role in neuronal signaling, excitotoxicity, and neurotransmission. Its caged structure allows for controlled activation of the NMDA receptor.
What are the CAS number and molecular formula for Caged MK801?
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The CAS number for Caged MK801 is 217176-91-5, and its molecular formula is C26H24N2O6.
What grade and purity does Tech Serve Solutions supply for Caged MK801?
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Tech Serve Solutions supplies Caged MK801 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is intended for research purposes.
What are the safety and handling recommendations for Caged MK801?
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Caged MK801 is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, including gloves and eye protection, and avoid inhalation or ingestion. Store in a cool, dark place at 2-8°C.
How is Caged MK801 packed, shipped, and exported?
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Caged MK801 is typically supplied as a white to light yellow powder. Tech Serve Solutions adheres to all relevant regulations for the safe packing, shipping, and export of fine chemicals globally.
How can I request a sample or a quote for Caged MK801?
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To request a sample or a quote for Caged MK801, please contact our sales department through the website or by phone. Our team will be happy to assist you with your inquiry.
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