Calcipotriol hydrate
Calcipotriol hydrate (CAS: 112965-21-6), with the empirical formula C27H40O3 · xH2O and a molecular weight of 412.60 (anhydrous basis), is a synthetic vitamin D3 analogue. This white to off-white solid is primarily utilised in cell biology research, particularly in studies related to cell signalling, gene regulation, and hormone pathways. Its specific biological activity makes it a valuable tool for investigating cellular differentiation and proliferation.
- IUPAC
- (5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol,Calcipotriene
- Synonyms
- Calcipotriene(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1alpha,3beta,24-triol
.png&w=3840&q=75)
Cell Biology Research
Calcipotriol hydrate serves as a crucial reagent in cell biology for investigating vitamin D receptor signalling pathways. It aids in understanding cellular processes like differentiation, proliferation, and apoptosis in various cell types.
Gene Regulation Studies
This compound is employed in research focused on gene expression and regulation, particularly concerning genes modulated by vitamin D. It helps elucidate the mechanisms by which vitamin D analogues influence transcriptional activity.
Hormone and Receptor Signalling
Calcipotriol hydrate is utilised to study the complex interactions within hormone signalling pathways and the function of steroid hormone receptors. Its structural similarity to endogenous vitamin D allows for targeted investigations.
| Molecular weight | 412.60 (anhydrous basis) |
|---|---|
| Empirical formula | C27H40O3 · xH2O |
| Assay | ≥99% (HPLC) |
| Form | solid |
| Solubility | DMSO: ≥24 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H310Fatal in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P302IF ON SKIN
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Calcipotriol hydrate used for?
+
Calcipotriol hydrate is primarily used in scientific research for cell biology studies, including investigations into cell signalling, gene regulation, and hormone pathways. It is a vitamin D3 analogue used as a research reagent.
What are the CAS number and formula for Calcipotriol hydrate?
+
The CAS number for Calcipotriol hydrate (anhydrous) is 112965-21-6. The empirical formula is C27H40O3 · xH2O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Calcipotriol hydrate with an assay of ≥99% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, or EP grade.
How should Calcipotriol hydrate be handled safely?
+
Calcipotriol hydrate is classified as a Danger substance. Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, faceshields, and gloves. Avoid dust formation and inhalation. It is classified with hazards H310 (Fatal in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
Is Calcipotriol hydrate a controlled substance?
+
The provided data does not indicate that Calcipotriol hydrate is a controlled substance.
How is Calcipotriol hydrate shipped and exported?
+
Calcipotriol hydrate is shipped and exported by Tech Serve Solutions according to standard chemical handling and international shipping regulations. It is typically stored at room temperature. Please contact us for specific shipping details for your region.
How can I request a quote or sample?
+
To request a quote or sample of Calcipotriol hydrate, please visit the 'Contact Us' section of our website or contact our sales team directly. We will be pleased to assist you with your inquiry.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis