4-Bromothiophene-3-carbonyl chloride
4-Bromothiophene-3-carbonyl chloride (CAS: 72899-51-5) is a halogenated heterocyclic compound with the empirical formula C5H2BrClOS and a molecular weight of 225.49 g/mol. This thiophene derivative serves as a valuable building block in organic synthesis. It is particularly useful for introducing the 4-bromothiophene-3-carbonyl moiety into more complex molecular structures, facilitating the development of novel compounds in research and chemical development.

Organic Synthesis Intermediate
4-Bromothiophene-3-carbonyl chloride is employed as a key intermediate in the synthesis of various organic compounds. Its reactive acyl chloride group allows for straightforward derivatisation through reactions with nucleophiles like alcohols, amines, and thiols.
Heterocyclic Chemistry
This compound is a useful reagent in heterocyclic chemistry, enabling the construction of thiophene-containing molecules. These structures are often found in pharmaceuticals, agrochemicals, and materials science applications.
Building Block for Pharmaceutical Research
The thiophene scaffold is present in numerous biologically active molecules. 4-Bromothiophene-3-carbonyl chloride can be used to synthesise novel drug candidates or modify existing lead compounds for improved therapeutic properties.
| Molecular weight | 225.49 |
|---|---|
| Empirical formula | C5H2BrClOS |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromothiophene-3-carbonyl chloride used for?
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4-Bromothiophene-3-carbonyl chloride is used as a building block and intermediate in organic synthesis, particularly for introducing the 4-bromothiophene-3-carbonyl group into more complex molecules. It finds applications in heterocyclic chemistry and pharmaceutical research.
What are the CAS number and formula for 4-Bromothiophene-3-carbonyl chloride?
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The CAS number for 4-Bromothiophene-3-carbonyl chloride is 72899-51-5, and its empirical formula is C5H2BrClOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromothiophene-3-carbonyl chloride with a purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Bromothiophene-3-carbonyl chloride be handled?
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According to GHS, 4-Bromothiophene-3-carbonyl chloride is classified with a Warning signal word and carries the hazard statement H319, indicating it causes serious eye irritation. Handle with appropriate personal protective equipment, including eye protection, and avoid contact with eyes. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
Can Tech Serve Solutions export 4-Bromothiophene-3-carbonyl chloride?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Bromothiophene-3-carbonyl chloride, serving customers worldwide.
How can I request a sample or quote for 4-Bromothiophene-3-carbonyl chloride?
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To request a sample or a quote for 4-Bromothiophene-3-carbonyl chloride, please contact our sales team through the website or by calling us directly. Please provide your contact details and the quantity required.
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