Bromoform
Bromoform (CHBr₃, CAS: 75-25-2), also known as Tribromomethane, is a dense, halogenated hydrocarbon with a molecular weight of 252.73 g/mol. This colourless liquid, often stabilized with approximately 1% ethanol, is primarily used as a chemical intermediate and in specific laboratory applications for genotoxicity assessments. Its distinct properties necessitate careful handling due to its hazardous nature.
- IUPAC
- Tribromomethane
- Synonyms
- Tribromomethane
Chemical Synthesis Intermediate
Bromoform serves as a valuable building block in organic synthesis. Its reactive nature allows for its incorporation into more complex molecular structures, facilitating the creation of novel compounds for various research and industrial purposes.
Genotoxicity Research
Historically, Bromoform has been utilised in laboratory settings to evaluate the genotoxic potential of related halogenated hydrocarbons. This application aids in understanding the toxicological profiles of such compounds.
Laboratory Reagent
As a chemical reagent, Bromoform can be employed in specific analytical procedures or as a solvent in specialized laboratory investigations where its physical and chemical properties are advantageous.
| Molecular weight | 252.73 |
|---|---|
| Empirical formula | CHBr3 |
| Assay | ≥95.0% (GC) |
| Boiling point | 146-150 °C(lit.) |
| Density | 2.89 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.595(lit.) |
| Vapour pressure | 5 mmHg (20 °C) |
| Melting point | 5-8 °C(lit.) |
| Vapour density | 8.7 (vs air) |
| Contains / stabiliser | ~1% ethanol as stabilizer |
| Application | Bromoform was used to evaluate the genotoxicity of chlorodibromomethane, bromodichloromethane and bromoform1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2515 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 22-23-36/38-51/53 |
| Safety statements (S) | 26-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bromoform primarily used for?
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Bromoform (CHBr₃, CAS: 75-25-2) is primarily used as a chemical intermediate in organic synthesis and in laboratory research for genotoxicity assessments.
What is the CAS number and formula for Bromoform?
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The CAS number for Bromoform is 75-25-2, and its empirical formula is CHBr₃.
What grade and purity does Tech Serve Solutions supply for Bromoform?
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Tech Serve Solutions supplies Bromoform with an assay of ≥95.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Bromoform be handled safely?
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Bromoform is a hazardous substance (GHS06, GHS09) with Danger signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and is toxic if inhaled (H331), while also being toxic to aquatic life with long lasting effects (H411). Appropriate personal protective equipment, including eyeshields, face shields, and suitable respiratory protection (e.g., type ABEK respirator filter), must be used. Handle only in well-ventilated areas or under a fume hood.
Is Bromoform a controlled substance?
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Bromoform (CAS 75-25-2) is listed as a List I chemical by the U.S. Drug Enforcement Administration (DEA) due to its potential use in illicit drug manufacturing. Appropriate diligence and documentation are required for its purchase and handling in relevant jurisdictions.
How is Bromoform packed, shipped, and exported?
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Bromoform is packed and shipped in compliance with relevant transportation regulations for hazardous materials (UN 2515, Class 6.1, PGIII). Tech Serve Solutions, a global supplier and exporter, ensures adherence to all international shipping requirements.
How can I request a quote or sample of Bromoform?
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To request a quote or sample for Bromoform, please contact our sales team through the website or by phone. Provide your specific requirements, and we will respond promptly.
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