Boron tris(trifluoroacetate) solution
Boron tris(trifluoroacetate) solution, CAS 350-70-9, with the linear formula (CF3CO2)3B and a molecular weight of 349.86 g/mol, is supplied by Tech Serve Solutions as a 1.0 M solution in trifluoroacetic acid. This reagent is primarily utilised as a reactant for the trifluoroacetylation of arenes. Its corrosive nature necessitates careful handling according to strict safety protocols.
- IUPAC
- BTFA,Tris[trifluoroacetoxy]borane
- Synonyms
- BTFATris[trifluoroacetoxy]borane

Trifluoroacetylation of Arenes
Boron tris(trifluoroacetate) solution serves as an effective reagent for the introduction of trifluoroacetyl groups onto aromatic rings. This transformation is crucial in organic synthesis for modifying the electronic and steric properties of arene compounds.
Chemical Synthesis
As a versatile synthetic reagent, this compound facilitates various chemical transformations. Its application extends to the preparation of complex organic molecules and functionalised intermediates in research and development settings.
Protection and Derivatization
The reagent can be employed in protection and derivatization strategies within multi-step syntheses. The trifluoroacetyl group can serve as a temporary protecting group or as a functional handle for further chemical manipulations.
| Molecular weight | 349.86 |
|---|---|
| Linear formula | (CF3CO2)3B |
| Density | 1.521 g/mL at 25 °C |
| Concentration | 1.0 M in trifluoroacetic acid |
| Application | Reactant for:• Trifluoroacetylation of arenes1 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 1742 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boron tris(trifluoroacetate) solution used for?
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Boron tris(trifluoroacetate) solution (CAS 350-70-9) is primarily used as a reactant for the trifluoroacetylation of arenes in organic synthesis.
What is the CAS number and formula for Boron tris(trifluoroacetate) solution?
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The CAS number is 350-70-9 and the linear formula is (CF3CO2)3B.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boron tris(trifluoroacetate) solution at a concentration of 1.0 M in trifluoroacetic acid. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should Boron tris(trifluoroacetate) solution be handled safely?
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This compound is corrosive (H314) and requires careful handling. Wear appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling instructions.
How is Boron tris(trifluoroacetate) solution shipped?
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Boron tris(trifluoroacetate) solution is classified under UN 1742, hazard class 8, Packing Group II, indicating it is a corrosive material requiring specialised shipping procedures. TSS ensures compliant packaging and export.
How can I request a sample or quote for Boron tris(trifluoroacetate) solution?
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To request a sample or a quote, please contact our sales department through the TSS website or by phone, providing the product name, CAS number (350-70-9), and desired quantity.
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