Borane tetrahydrofuran complex solution
Borane tetrahydrofuran complex solution (CAS: 14044-65-6, Formula: BH3OC4H8, MW: 85.94) is a versatile reducing agent stabilised with N-Isopropyl-N-methyl-tert-butylamine for enhanced safety. Supplied as a 1.0 M solution in tetrahydrofuran, it is primarily used in chemical synthesis for selective reductions of various functional groups. Its handling requires strict adherence to safety protocols due to its flammability and reactivity.
Selective Reduction Agent
This borane complex is extensively employed in organic synthesis for the selective reduction of functional groups such as aldehydes, ketones, carboxylic acids, and imines. Its controlled reactivity allows for high yields and chemoselectivity in complex molecular transformations.
Hydroboration Reactions
Borane tetrahydrofuran complex serves as a key reagent in hydroboration-oxidation sequences, a crucial method for the anti-Markovnikov addition of water across double and triple bonds. This process is vital for synthesizing alcohols and other oxygenated compounds.
Amination and Synthesis of Amines
It facilitates reductive amination processes and is used in the synthesis of primary and secondary amines from corresponding carbonyl compounds. This application is significant in the pharmaceutical and agrochemical industries.
Stabilised Borane Reagent
The NIMBA-stabilised formulation offers improved handling characteristics compared to neat diborane or less stable borane complexes, mitigating risks associated with pyrophoricity and decomposition.
| Molecular weight | 85.94 |
|---|---|
| Linear formula | BH3OC4H8 |
| Density | 0.880 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
| Storage temperature | 2-8°C |
| Contains / stabiliser | 0.005 M N-Isopropyl-N-methyl-tert-butylamine as stabilizer |
| Application | New, Safer, NIMBA-Stabilized BH3 THF Solutions |
Hazard statements
- H225Highly flammable liquid and vapour
- H260In contact with water releases flammable gases
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P223Do not allow contact with water
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P370In case of fire
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -20 °C / -4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-14/15-19-36/37 |
| Safety statements (S) | 16-26-43 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Borane tetrahydrofuran complex solution used for?
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Borane tetrahydrofuran complex solution (CAS 14044-65-6) is primarily used as a selective reducing agent in organic synthesis, particularly for the reduction of aldehydes, ketones, and carboxylic acids, and in hydroboration reactions.
What is the CAS number and formula for Borane tetrahydrofuran complex solution?
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The CAS number is 14044-65-6, and the chemical formula is BH3OC4H8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Borane tetrahydrofuran complex solution at a concentration of 1.0 M in THF, stabilised with 0.005 M N-Isopropyl-N-methyl-tert-butylamine. TSS does not represent this product as USP, BP, or EP grade.
How should Borane tetrahydrofuran complex solution be handled safely?
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Borane tetrahydrofuran complex solution is highly flammable (flash point -20 °C) and reacts with water. It may form explosive peroxides and can cause severe eye irritation and respiratory irritation. Handle under an inert atmosphere, away from ignition sources, and wear appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator.
Is Borane tetrahydrofuran complex solution regulated or controlled?
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Based on the provided data, there is no indication that Borane tetrahydrofuran complex solution (CAS 14044-65-6) is a controlled or scheduled substance. However, regulations can vary by jurisdiction.
How is Borane tetrahydrofuran complex solution packed and shipped?
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This product is typically shipped as UN 3399, Hazard Class 4.3, Packing Group I, indicating it is a substance that in contact with water emits flammable gases and is dangerous if wet. It requires specialised handling and shipping procedures.
How can I request a sample or quote?
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To request a sample or a quote for Borane tetrahydrofuran complex solution, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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