Boc-Tyr-OSu
N-alpha-Boc-L-Tyrosine hydroxysuccinimide ester (CAS: 20866-56-2) is a protected amino acid derivative with the molecular formula C18H22N2O7 and a molecular weight of 378.38. This compound serves as a crucial intermediate in peptide synthesis, enabling the controlled introduction of tyrosine residues into peptide chains. Its primary application lies in chemical and biochemical research, facilitating the construction of complex peptides and peptidomimetics for various scientific investigations.
- IUPAC
- Boc-L-tyrosine hydroxysuccinimide ester
- Synonyms
- N-alpha-Boc-L-Tyrosine hydroxysuccinimide ester

Peptide Synthesis
Boc-Tyr-OSu is widely utilized in solid-phase and solution-phase peptide synthesis as an activated tyrosine derivative. The Boc protecting group on the alpha-amino function and the N-hydroxysuccinimide ester facilitate controlled coupling reactions.
Biochemical Research
It is employed in chemical biology to incorporate modified tyrosine residues into peptides and proteins for studying structure-function relationships, protein-protein interactions, or as enzyme substrates.
Chemical Synthesis
This compound acts as a versatile building block in the synthesis of complex organic molecules and peptidomimetics, where precise control over amino acid incorporation is essential.
| Molecular weight | 378.38 |
|---|---|
| Empirical formula | C18H22N2O7 |
| Assay | ≥99.0% (N) |
| Optical activity | [α]20/D −13±1°, c = 1% in dioxane |
| Storage temperature | −20°C |
| Melting point | ~190 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Tyr-OSu used for?
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Boc-Tyr-OSu (N-alpha-Boc-L-Tyrosine hydroxysuccinimide ester) is primarily used as an activated intermediate in peptide synthesis and in chemical biology research for incorporating tyrosine residues.
What is the CAS number and molecular formula for Boc-Tyr-OSu?
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The CAS number is 20866-56-2, and the molecular formula is C18H22N2O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Tyr-OSu with an assay of ≥99.0% (N). We do not represent this product as USP, BP, or EP grade.
How should Boc-Tyr-OSu be handled and stored?
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Handle Boc-Tyr-OSu with appropriate personal protective equipment, including eyeshields and gloves. A P1 (EN143) or N95 (US) respirator filter is recommended. It should be stored at -20°C to maintain its stability and efficacy.
Is Boc-Tyr-OSu a hazardous substance?
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According to the WGK classification, this substance is rated 3, indicating it is hazardous to water. Appropriate safety precautions must be taken during handling and disposal.
How is Boc-Tyr-OSu packed, shipped, and exported?
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Tech Serve Solutions safely packs and ships fine chemicals, including Boc-Tyr-OSu, adhering to international regulations for chemical export. Specific packaging details are available upon request.
How can I request a sample or a quote for Boc-Tyr-OSu?
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To request a sample or a quote for Boc-Tyr-OSu, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
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