Boc-D-phenylalaninol

CAS 106454-69-7C6H5CH2CH[NHCO2C(CH3)3]CH2OHChemical Synthesis

Boc-D-phenylalaninol (CAS: 106454-69-7) is a protected amino alcohol derivative with the linear formula C 6 H 5 CH 2 CH[NHCO 2 C(CH 3 ) 3 ]CH 2 OH and a molecular weight of 251.32 g/mol. This compound serves as a valuable chiral building block in organic synthesis, particularly in the development of complex molecules and pharmaceutical intermediates. Its protected nature allows for selective chemical transformations, making it a key reagent in peptide chemistry and drug discovery research.

IUPAC: (R)-(+)-2-(tert-Butoxycarbonylamino)-3-phenyl-1-propanol,(R)-2-(Boc-amino)-3-phenyl-1-propanol,N-(tert-Butoxycarbonyl)-D-phenylalaninol
Synonyms: (R)-(+)-2-(tert-Butoxycarbonylamino)-3-phenyl-1-propanol(R)-2-(Boc-amino)-3-phenyl-1-propanolN-(tert-Butoxycarbonyl)-D-phenylalaninol

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Boc-D-phenylalaninol (C6H5CH2CH[NHCO2C(CH3)3]CH2OH) — chemical structure, CAS 106454-69-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAmino AlcoholsChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Chiral Building Block in Organic Synthesis

Boc-D-phenylalaninol is widely employed as a chiral synthon for the construction of complex organic molecules. Its stereochemistry is preserved during synthetic procedures, enabling the creation of enantiomerically pure target compounds.

Pharmaceutical Intermediate Synthesis

The compound is instrumental in the synthesis of various pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its structure lends itself to incorporation into molecules targeting diverse therapeutic areas.

Peptide Chemistry

As a derivative of D-phenylalanine, Boc-D-phenylalaninol finds application in peptide synthesis, particularly for non-natural peptides or peptidomimetics requiring specific structural modifications or enhanced stability.

Research and Development

This reagent is essential for academic and industrial research laboratories exploring novel chemical entities and synthetic methodologies. It is a fundamental tool in chemical biology and drug discovery programmes.

02 /Properties

Molecular weight	251.32
Linear formula	C6H5CH2CH[NHCO2C(CH3)3]CH2OH
Assay	≥99.0% (sum of enantiomers, TLC)
Optical activity	[α]20/D +27±2°, c = 1% in methanol
Storage temperature	2-8°C
Melting point	95-98 °C(lit.)95-98 °C

03 /Identifiers & registry

CAS number

106454-69-7

Beilstein registry

4686134

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Boc-D-phenylalaninol used for?

Boc-D-phenylalaninol is primarily used as a chiral building block in organic synthesis, a pharmaceutical intermediate, and in peptide chemistry research and development.

What is the CAS number and chemical formula for Boc-D-phenylalaninol?

The CAS number for Boc-D-phenylalaninol is 106454-69-7. Its linear chemical formula is C 6 H 5 CH 2 CH[NHCO 2 C(CH 3 ) 3 ]CH 2 OH.

What grade and purity does Tech Serve Solutions supply for Boc-D-phenylalaninol?

Tech Serve Solutions supplies Boc-D-phenylalaninol with an assay of ≥99.0% (sum of enantiomers, TLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Boc-D-phenylalaninol be handled and stored?

Boc-D-phenylalaninol has a WGK Germany classification of 3, indicating it is hazardous to water. It should be handled with appropriate personal protective equipment in a well-ventilated area. Recommended storage is at 2-8°C.

Is Boc-D-phenylalaninol a controlled substance?

The provided data does not indicate that Boc-D-phenylalaninol is a controlled substance.

How can I request a quote or sample for Boc-D-phenylalaninol?

To request a quote or sample of Boc-D-phenylalaninol, please contact our sales team through the website or by calling our office. We handle global packing, shipping, and export.