2-Methyl-2-phenylpropylmagnesium chloride solution
2-Methyl-2-phenylpropylmagnesium chloride solution (CAS 35293-35-7), with the linear formula C<sub>6</sub>H<sub>5</sub>C(CH<sub>3</sub>)<sub>2</sub>CH<sub>2</sub>MgCl and a molecular weight of 192.97 g/mol, is a Grignard reagent. This organometallic compound is supplied in a 0.5 M solution in diethyl ether. It serves as a valuable building block in organic synthesis, particularly for the introduction of the 2-methyl-2-phenylpropyl group into various molecules.
Organometallic Synthesis
Utilised as a Grignard reagent, this compound facilitates carbon-carbon bond formation by reacting with electrophiles such as aldehydes, ketones, esters, and epoxides. Its specific structure allows for the introduction of a branched alkyl aryl moiety in complex molecule synthesis.
Pharmaceutical Intermediate Preparation
This reagent can be employed in the multi-step synthesis of complex organic molecules that may serve as pharmaceutical intermediates. Its reactivity profile is useful for constructing specific carbon skeletons required in drug discovery and development.
Fine Chemical Manufacturing
As a versatile organometallic reagent, it finds application in the production of specialised fine chemicals. The controlled reaction conditions allow for precise functionalisation and elaboration of organic structures.
| Molecular weight | 192.97 |
|---|---|
| Linear formula | C6H5C(CH3)2CH2MgCl |
| Boiling point | 34.6 °C |
| Density | 0.766 g/mL at 25 °C |
| Concentration | 0.5 M in diethyl ether |
Hazard statements
- H224Extremely flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -27 °C / -16.6 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F+,C |
| Risk statements (R) | 12-14-19-22-34-67 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyl-2-phenylpropylmagnesium chloride solution used for?
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This Grignard reagent is primarily used in organic synthesis for the formation of carbon-carbon bonds, enabling the introduction of the 2-methyl-2-phenylpropyl group into target molecules. It is valuable in the preparation of pharmaceutical intermediates and fine chemicals.
What are the CAS number and formula for 2-Methyl-2-phenylpropylmagnesium chloride solution?
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The CAS number is 35293-35-7, and the linear formula is C<sub>6</sub>H<sub>5</sub>C(CH<sub>3</sub>)<sub>2</sub>CH<sub>2</sub>MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in diethyl ether. TSS does not represent it as USP, BP, or EP grade; it is suitable for research and general laboratory synthesis.
What are the key safety and handling considerations?
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This is a highly flammable liquid and vapour (H224) that is harmful if swallowed (H302), causes severe skin burns and eye damage (H314), and may cause drowsiness or dizziness (H336). It reacts violently with water and may form explosive peroxides. Handle with extreme care in a well-ventilated area, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Keep away from heat, sparks, and open flames.
How is this chemical packed, shipped, and exported?
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As a hazardous material, it is packed and shipped in compliance with international transportation regulations. Tech Serve Solutions offers global export services for this product.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or a detailed quotation for 2-Methyl-2-phenylpropylmagnesium chloride solution.
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