Boc-D-valinol
Boc-D-valinol (CAS: 106391-87-1), a protected chiral amino alcohol, is crucial in organic synthesis. Its N-Boc protecting group facilitates controlled reactions, making it invaluable in constructing complex molecules. This compound is widely employed in peptide chemistry and as a building block for pharmaceuticals and other fine chemicals, where stereochemical integrity is paramount.
- IUPAC
- N-(tert-Butoxycarbonyl)-D-valinol
- Synonyms
- N-(tert-Butoxycarbonyl)-D-valinol
![Boc-D-valinol ((CH3)2CHCH[NHCO2C(CH3)3]CH2OH) — chemical structure, CAS 106391-87-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F106391-87-1.png&w=3840&q=75)
Peptide Synthesis
Boc-D-valinol serves as a chiral building block in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the precise construction of peptide chains with defined stereochemistry.
Pharmaceutical Intermediates
This compound is utilised in the synthesis of various pharmaceutical intermediates. Its chiral nature is essential for creating stereospecific active pharmaceutical ingredients (APIs).
Chiral Ligand Synthesis
Boc-D-valinol can be used as a precursor in the development of chiral ligands for asymmetric catalysis, contributing to enantioselective synthesis in organic chemistry.
Chemical Biology Research
In chemical biology, it functions as a tool for creating modified biomolecules or as a component in the development of probes and diagnostic agents.
| Molecular weight | 203.28 |
|---|---|
| Linear formula | (CH3)2CHCH[NHCO2C(CH3)3]CH2OH |
| Assay | 98% |
| Boiling point | 218 °C |
| Density | 0.995 g/mL at 25 °C |
| Refractive index | n20/D 1.451(lit.) |
| Optical activity | [α]23/D +23°, c = 1 in chloroform |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-valinol used for?
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Boc-D-valinol is primarily used as a chiral building block in organic synthesis, particularly in peptide chemistry, and as an intermediate for pharmaceuticals and other fine chemicals.
What is the CAS number and formula for Boc-D-valinol?
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The CAS number for Boc-D-valinol is 106391-87-1. Its linear formula is (CH3)2CHCH[NHCO2C(CH3)3]CH2OH, and its molecular weight is 203.28.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-valinol with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.
What are the safety and handling precautions for Boc-D-valinol?
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Boc-D-valinol is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is Boc-D-valinol packed, shipped, and exported?
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Boc-D-valinol is carefully packed according to industry standards to ensure stability during transit. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for Boc-D-valinol?
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To request a sample or a quote for Boc-D-valinol, please contact our sales team through the website or via the provided contact details, referencing the product name and CAS number.
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