Bisindolylmaleimide VIII acetate salt
Bisindolylmaleimide VIII acetate salt (CAS: 138516-31-1), with the molecular formula C24H22N4O2 · C2H4O2 and a molecular weight of 458.51 g/mol, is a potent inhibitor. This compound primarily functions as a protein kinase C (PKC) inhibitor and is valuable in cell biology research. It is widely employed in studies of cell signaling pathways, particularly those involving neuroscience and enzyme inhibition. Its acetate salt form enhances solubility for experimental applications.
- IUPAC
- Ro 31-7549 acetate

Protein Kinase C Inhibition
Bisindolylmaleimide VIII acetate salt is a well-characterised inhibitor of Protein Kinase C (PKC) isozymes. It serves as a crucial research tool for elucidating the roles of PKC in various cellular processes.
Cell Signaling Research
This compound is utilized to investigate signal transduction pathways regulated by protein kinases. Its specific activity makes it valuable in understanding cellular responses, particularly in neuroscience and cell biology contexts.
Enzyme Inhibitor Studies
As a selective enzyme inhibitor, Bisindolylmaleimide VIII acetate salt is employed in biochemical assays to study enzyme kinetics and mechanisms. It aids in the development of novel therapeutic strategies by profiling kinase activity.
| Molecular weight | 458.51 |
|---|---|
| Empirical formula | C24H22N4O2 · C2H4O2 |
| Assay | ≥93% (H-NMR) |
| Solubility | DMSO: solubleH2O: solublemethanol: soluble |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bisindolylmaleimide VIII acetate salt used for?
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Bisindolylmaleimide VIII acetate salt is primarily used as a research tool for inhibiting protein kinase C (PKC) and studying cell signaling pathways, particularly in cell biology and neuroscience research.
What is the CAS number and formula for Bisindolylmaleimide VIII acetate salt?
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The CAS number for Bisindolylmaleimide VIII acetate salt is 138516-31-1, and its formula is C24H22N4O2 · C2H4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bisindolylmaleimide VIII acetate salt with an assay of ≥93% (H-NMR). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Bisindolylmaleimide VIII acetate salt be handled?
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Handle Bisindolylmaleimide VIII acetate salt with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Ensure adequate ventilation. The WGK Germany is 3.
How is Bisindolylmaleimide VIII acetate salt packed and shipped?
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Bisindolylmaleimide VIII acetate salt is stored at -20°C. TSS exports and supplies this chemical globally, adhering to all relevant shipping regulations for fine chemicals.
How can I request a quote or sample for Bisindolylmaleimide VIII acetate salt?
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To request a quote or sample of Bisindolylmaleimide VIII acetate salt, please contact our sales team through the TSS website or by calling our customer service line.
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